User profiles for S. Mucha

Sebastian Mucha

Scotland's Rural College
Verified email at jay.up.poznan.pl
Cited by 919

[HTML][HTML] Animal Board Invited Review: Meta-analysis of genetic parameters for resilience and efficiency traits in goats and sheep

S Mucha, F Tortereau, A Doeschl-Wilson, R Rupp… - animal, 2022 - Elsevier
Genetic selection focused purely on production traits has proven very successful in
improving the productive performance of livestock. However, heightened environmental and …

[HTML][HTML] Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants

…, T Konopka, L Li, L Ma, T Meitinger, S Mucha… - Nature …, 2022 - nature.com
The discovery of genetic loci associated with complex diseases has outpaced the elucidation
of mechanisms of disease pathogenesis. Here we conducted a genome-wide association …

[HTML][HTML] Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants

…, HW Lim, A Metspalu, U Mrowietz, S Mucha… - Nature …, 2017 - nature.com
… We employed Duffy’s approach to adjust odds ratios and se's for bias caused by response
misclassification in logistic regression 24 . If β* and V(β*) are the naive log OR and its …

Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease

SG Ji, BD Juran, S Mucha, T Folseraas, L Jostins… - Nature …, 2017 - nature.com
Primary sclerosing cholangitis (PSC) is a rare progressive disorder leading to bile duct
destruction; ∼75% of patients have comorbid inflammatory bowel disease (IBD). We undertook …

[HTML][HTML] Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility

…, S Mucha, M Weichenthal, S Weidinger… - Nature …, 2015 - nature.com
Psoriasis is a common inflammatory skin disease with complex genetics and different degrees
of prevalence across ethnic populations. Here we present the largest trans-ethnic genome…

Molecule attention transformer

…, S Mucha, K Rataj, J Tabor, S Jastrzębski - arXiv preprint arXiv …, 2020 - arxiv.org
Designing a single neural network architecture that performs competitively across a range of
molecule property prediction tasks remains largely an open challenge, and its solution may …

Genomic application in sheep and goat breeding

R Rupp, S Mucha, H Larroque, J McEwan… - Animal …, 2016 - pure.sruc.ac.uk
… Sebastian Mucha is a post-doctoral researcher at the Scotland’s Rural College (SRUC). He
undertakes genomic research for applied livestock programs in sheep and goats. He mainly …

Nasal challenge with allergen leads to maxillary sinus inflammation

FM Baroody, SM Mucha, M Detineo… - Journal of allergy and …, 2008 - Elsevier
BACKGROUND: Allergic rhinitis and chronic rhinosinusitis are both characterized by chronic
inflammation. OBJECTIVE: We sought to investigate the effect of nasal allergen challenge …

[HTML][HTML] Genetic analysis of milk urea nitrogen and relationships with yield and fertility across lactation

S Mucha, E Strandberg - Journal of Dairy Science, 2011 - Elsevier
The aim of this project was to investigate the relationship of milk urea nitrogen (MUN) with 3
milk production traits [milk yield (MY), fat yield (FY), protein yield (PY)] and 6 fertility …

[HTML][HTML] Psoriasis and cardiometabolic traits: modest association but distinct genetic architectures

…, M Weichenthal, S Mucha, S Schreiber… - Journal of Investigative …, 2015 - Elsevier
Psoriasis has been linked to cardiometabolic diseases, but epidemiological findings are
inconsistent. We investigated the association between psoriasis and cardiometabolic outcomes …