User profiles for S. Lemieux

Sebastien Lemieux

IRIC, Biochemistry and Mila, Université de Montréal
Verified email at umontreal.ca
Cited by 8623

A comprehensive map of the mTOR signaling network

…, M Therrien, S Lemieux… - Molecular systems …, 2010 - embopress.org
The mammalian target of rapamycin (mTOR) is a central regulator of cell growth and proliferation.
mTOR signaling is frequently dysregulated in oncogenic cells, and thus an attractive …

Effects of dietary factors on oxidation of low-density lipoprotein particles

A Lapointe, C Couillard, S Lemieux - The Journal of Nutritional Biochemistry, 2006 - Elsevier
Oxidized low-density lipoproteins (ox-LDLs) appear to play a significant role in atherogenesis.
In fact, circulating ox-LDL concentrations have been recognized as a risk factor for …

Waist circumference and abdominal sagittal diameter: best simple anthropometric indexes of abdominal visceral adipose tissue accumulation and related …

MC Pouliot, JP Després, S Lemieux, S Moorjani… - The American journal of …, 1994 - Elsevier
… as important in the evaluation of the patient’s cardiovascular risk profile. Currently, the
waist-… disturbances associated with abdominal obesity.s*4 However, computed tomography is …

Licensing of natural killer cells by host major histocompatibility complex class I molecules

…, YJ Song, L Yang, AR French, JB Sunwoo, S Lemieux… - Nature, 2005 - nature.com
Self versus non-self discrimination is a central theme in biology from plants 1 to vertebrates,
and is particularly relevant for lymphocytes that express receptors capable of recognizing self…

Theano: A Python framework for fast computation of mathematical expressions

…, C Laurent, S Lee, S Lefrancois, S Lemieux… - arXiv e …, 2016 - ui.adsabs.harvard.edu
Theano is a Python library that allows to define, optimize, and evaluate mathematical expressions
involving multi-dimensional arrays efficiently. Since its introduction, it has been one of …

[HTML][HTML] Can eating pleasure be a lever for healthy eating? A systematic scoping review of eating pleasure and its links with dietary behaviors and health

…, V Provencher, S Desroches, S Lemieux - PloS one, 2020 - journals.plos.org
The aims of this review were to map and summarize data currently available about 1) key
dimensions of eating pleasure; 2) associations of eating pleasure, and its key dimensions, with …

Large‐scale essential gene identification in Candida albicans and applications to antifungal drug discovery

…, S Veronneau, S Lemieux, S Kauffman… - Molecular …, 2003 - Wiley Online Library
… PCR amplification times were: 2 min at 94C, followed by five cycles of 30 s at 94C, 30 s at
55C, 1 min at 72C, an additional 25 cycles of 30 s at 94C, 30 s at 58C, 1 min at 72C and 7 min …

[HTML][HTML] Genomic Islands in the Pathogenic Filamentous Fungus Aspergillus fumigatus

…, BJ Haas, JM Inman, R Kent, S Lemieux… - PLoS …, 2008 - journals.plos.org
We present the genome sequences of a new clinical isolate of the important human pathogen,
Aspergillus fumigatus, A1163, and two closely related but rarely pathogenic species, …

Effects of acute changes of plasma free fatty acids on intramyocellular fat content and insulin resistance in healthy subjects

G Boden, B Lebed, M Schatz, C Homko, S Lemieux - Diabetes, 2001 - Am Diabetes Assoc
The reason for the 3- to 4-h delay between a rise in plasma free fatty acid (FFA) levels and
the development of insulin resistance remains unknown. In the current study, we have tested …

Sex differences in the relation of visceral adipose tissue accumulation to total body fatness

S Lemieux, D Prud'homme, C Bouchard… - The American journal of …, 1993 - Elsevier
The associations between the amount of abdominal adipose tissue (AT) measured by computed
tomography (CT) or estimated with predictive equations and the amount of total body fat …