User profiles for S. Lagger
Sabine LaggerUniversity Assistant, PostDoc, Vetmeduni Vienna Verified email at vetmeduni.ac.at Cited by 1847 |
[PDF][PDF] Histone deacetylase 1 and 2-controlled embryonic development and cell differentiation.
… To ask, whether the lethal phenotype of HDAC2 knockout mice reflects a cell-autonomous
function of HDAC2 in cardiomyocytes Eric Olson’s group conditionally deleted the HDAC2 …
function of HDAC2 in cardiomyocytes Eric Olson’s group conditionally deleted the HDAC2 …
[HTML][HTML] The role of activator protein-1 (AP-1) family members in CD30-positive lymphomas
… , accelerates the transition from G1 to S phase [17]. On the other hand, JUNB negatively
regulates cell proliferation by inhibiting the progression into S phase via activation of the CDKI …
regulates cell proliferation by inhibiting the progression into S phase via activation of the CDKI …
Chromium bioaccumulation: comparison of the capacity of two floating aquatic macrophytes
MA Maine, NL Suñé, SC Lagger - Water Research, 2004 - Elsevier
… The Cr distribution in aerial parts and roots of S. herzogii and P. … S. herzogii showed a
higher growth rate than P. stratiotes at … The chlorophyll content in tissues was less affected in S. …
higher growth rate than P. stratiotes at … The chlorophyll content in tissues was less affected in S. …
The cyclin-dependent kinase inhibitor p21 is a crucial target for histone deacetylase 1 as a regulator of cellular proliferation
… suppressor leading to its inactivation and fast synthesis of S phase proteins (Citation15). …
Importantly, HDAC1 −/− cells displayed reduced numbers of cycling cells in S phase, while the …
Importantly, HDAC1 −/− cells displayed reduced numbers of cycling cells in S phase, while the …
PDGFR blockade is a rational and effective therapy for NPM-ALK–driven lymphomas
… Ostman for helpful discussions and technical help with PDGFRB analysis, and S. Reichmann
for technical help with soluble-CD30 and PDGFB assays. LK is supported by the Fonds zur …
for technical help with soluble-CD30 and PDGFB assays. LK is supported by the Fonds zur …
Distinct and redundant functions of histone deacetylases HDAC1 and HDAC2 in proliferation and tumorigenesis
J Jurkin, G Zupkovitz, S Lagger, R Grausenburger… - Cell cycle, 2011 - Taylor & Francis
Histone deacetylases (HDACs) are negative regulators of gene expression and have been
implicated in tumorigenesis and tumor progression. Therefore, HDACs are promising targets …
implicated in tumorigenesis and tumor progression. Therefore, HDACs are promising targets …
[HTML][HTML] MeCP2 recognizes cytosine methylated tri-nucleotide and di-nucleotide sequences to tune transcription in the mammalian brain
S Lagger, JC Connelly, G Schweikert, S Webb… - PLoS …, 2017 - journals.plos.org
… Our results re-emphasize MeCP2’s original proposed function as a transcriptional
repressor whose purpose is to maintain the delicate balance of neuronal gene expression. …
repressor whose purpose is to maintain the delicate balance of neuronal gene expression. …
[HTML][HTML] KMT2C methyltransferase domain regulated INK4A expression suppresses prostate cancer metastasis
… As p16 INK4A inhibits cell cycle progression at the G1/S transition, we performed fGSEA of
two sets of genes upregulated during this process (REACTOME G1/S, FISCHER G1/S) and …
two sets of genes upregulated during this process (REACTOME G1/S, FISCHER G1/S) and …
The molecular basis of variable phenotypic severity among common missense mutations causing Rett syndrome
K Brown, J Selfridge, S Lagger… - Human molecular …, 2016 - academic.oup.com
… levels in the presence of double-stranded oligonucleotides bearing specific modifications
of cytosine (S. Lagger et al., manuscript in preparation). The method has the advantage that it …
of cytosine (S. Lagger et al., manuscript in preparation). The method has the advantage that it …
The specific role of histone deacetylase 2 in adult neurogenesis
… After this incubation step reactions were stopped with 35 ml Histone Stop and 800 ml
ethylacetate followed by a vortex step of 15 s and spin down 4 min at 10,000 rpm in a swing out …
ethylacetate followed by a vortex step of 15 s and spin down 4 min at 10,000 rpm in a swing out …