User profiles for S. Kempa

stefan kempa

BIMSB@MDC Berlin-Buch
Verified email at mdc-berlin.de
Cited by 10794

Effect of sulfur availability on the integrity of amino acid biosynthesis in plants

…, M Bielecka, B Gakiere, S Krueger, J Rinder, S Kempa… - Amino acids, 2006 - Springer
Amino acid levels in plants are regulated by a complex interplay of regulatory circuits at the
level of enzyme activities and gene expression. Despite the diversity of precursors involved …

Salt-responsive gut commensal modulates TH17 axis and disease

…, R Dechend, M Kleinewietfeld, S Kempa… - Nature, 2017 - nature.com
… To compare more than two groups, we used one-way ANOVA followed by Tukey’s post
hoc test or Kruskal–Wallis test followed by Dunn’s post hoc test, as appropriate. Statistical …

[PDF][PDF] Dietary fatty acids directly impact central nervous system autoimmunity via the small intestine

…, M Kleinewietfeld, S Kempa, J Thöne, S Demir… - Immunity, 2015 - cell.com
… lymphocytes (LPLs), and Peyer’s patches (PPs) in various gut … ’s adjuvant (CFA) only (Figure
S5I). To further investigate whether metabolites of the gut microbiota are involved in LA’s

Towards dissecting nutrient metabolism in plants: a systems biology case study on sulphur metabolism

VJ Nikiforova, B Gakiere, S Kempa… - Journal of …, 2004 - academic.oup.com
… thaliana plants grown in hydroponic culture are either supplied with sulphur-sufficient Hoagland
medium or with Hoagland medium where sulphate has been exchanged with nitrate (−S

Synthetic lethal metabolic targeting of cellular senescence in cancer therapy

…, B Dörken, L Willmitzer, M Reimann, S Kempa, S Lee… - Nature, 2013 - nature.com
Activated oncogenes and anticancer chemotherapy induce cellular senescence, a terminal
growth arrest of viable cells characterized by S-phase entry-blocking histone 3 lysine 9 …

Short-chain fatty acid propionate protects from hypertensive cardiovascular damage

…, K Kusche-Vihrog, M Grandoch, J Fielitz, S Kempa… - Circulation, 2019 - Am Heart Assoc
… Stefan KempaS. Kempa performed and analyzed gas chromatography–mass
spectrometry measurements. Dr Krannich performed statistical analyses. Dr Wilck, H. …

[PDF][PDF] Glycolysis-mediated changes in acetyl-CoA and histone acetylation control the early differentiation of embryonic stem cells

…, T Scherf, M Nissim-Rafinia, S Kempa… - Cell metabolism, 2015 - cell.com
Loss of pluripotency is a gradual event whose initiating factors are largely unknown. Here we
report the earliest metabolic changes induced during the first hours of differentiation. High-…

The growing complexity of HIF-1α's role in tumorigenesis: DNA repair and beyond

N Rohwer, C Zasada, S Kempa, T Cramer - Oncogene, 2013 - nature.com
… In this review, we aim to acknowledge HIFα’s growing complexity by outlining its functional
relevance … , potentially resulting in more efficient clinical translation of HIF-1α’s pathobiology. …

[PDF][PDF] Propionic acid shapes the multiple sclerosis disease course by an immunomodulatory mechanism

…, K Stühler, F Hirche, A Balogh, S Kempa… - Cell, 2020 - cell.com
Short-chain fatty acids are processed from indigestible dietary fibers by gut bacteria and
have immunomodulatory properties. Here, we investigate propionic acid (PA) in multiple …

Transcriptome analysis of sulfur depletion in Arabidopsis thaliana: interlacing of biosynthetic pathways provides response specificity

V Nikiforova, J Freitag, S Kempa, M Adamik… - The Plant …, 2003 - Wiley Online Library
… The first morphological differences – slight growth retardation and chlorosis – between plants
on normal (+S) and sulfur-deficient medium (–S) were visible at day 11 of sulfur depletion …