To ensure the high-fidelity transmission of genetic information, cells have evolved mechanisms
to monitor genome integrity. Cells respond to DNA damage by activating a complex DNA-…

The prime objective for every life form is to deliver its genetic material, intact and unchanged,
to the next generation. This must be achieved despite constant assaults by endogenous …

Advancing age is characterized by impairment in the function of the many regulatory processes
that provide functional integration between cells and organs. Therefore, there may be a …

Background A safe and efficacious vaccine against severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), if deployed with high coverage, could contribute to the control of …

We report an improved draft nucleotide sequence of the 2.3-gigabase genome of maize, an
important crop plant and model for biological research. Over 32,000 genes were predicted, …

… billion-plus nucleotides, we approach an understanding of the plant’s capacity to turn
carbon dioxide, water, sunlight and elemental nitrogen and minerals into concentrated energy, …

… assessments of an individual’s experience corroborate the individual’s self-rating. Within the
job setting, a knowledgeable observer would be a person’s co-worker. Accordingly, a group …

Zircon megacrysts represent a late stage in the crystallisation of the magmas that produced
the low-Cr megacryst suite (Ol+Opx+Cpx+Gnt+Ilm+Phl+Zir) found in many kimberlites, and …

Within academia there has been similar growing awareness of this need. Although this
awareness is being articulated in several ways, one of the most frequent involves the …

BRCA1 and BRCA2 are important for DNA double-strand break repair by homologous
recombination 1 , and mutations in these genes predispose to breast and other cancers 2 . Poly(…