User profiles for S. Iyyanki

Tejaswi Sriranga Iyyanki

Sanofi
Verified email at sanofi.com
Cited by 1077

Integrative detection and analysis of structural variation in cancer genomes

…, Y Wang, R Clark, L Zhang, H Yang, T Liu, S Iyyanki… - Nature …, 2018 - nature.com
S phase of the cell cycle 39,40 . Genome-wide profiling of replication timing shows that these
domains can be replicated at different times during S … timing during development (S), using …

Noncoding genetic variation in GATA3 increases acute lymphoblastic leukemia risk through local and global changes in chromatin conformation

…, B Zhang, W Yang, V Perez-Andreu, J Xu, S Iyyanki… - Nature …, 2022 - nature.com
… So far, the exact variant that determines GWAS signaling at the GATA3 locus is unknown
and the exact molecular process by which the variant(s) contribute to Ph-like ALL pathogenesis …

Adipose-derived stem-cell-seeded non-cross-linked porcine acellular dermal matrix increases cellular infiltration, vascular infiltration, and mechanical strength of …

TS Iyyanki, LW Dunne, Q Zhang, J Hubenak… - … engineering Part A, 2015 - liebertpub.com
Adipose-derived stem cells (ASCs) facilitate wound healing by improving cellular and vascular
recruitment to the wound site. Therefore, we investigated whether ASCs would augment a …

Non-coding germline GATA3 variants alter chromatin topology and contribute to pathogenesis of acute lymphoblastic leukemia

…, B Zhang, W Yang, V Perez-Andreu, J Xu, S Iyyanki… - bioRxiv, 2020 - biorxiv.org
… process by which the variant(s) contribute to Ph-like ALL pathogenesis is also unclear. …
clinicians and research staff at St Jude Children’s Research Hospital and COG institutions. …

Silk fibroin nanoparticles and cancer therapy

D Mishra, TS Iyyanki, JR Hubenak, Q Zhang… - Nanotechnology in …, 2017 - Elsevier
Curcumin is a potent anticancer molecule naturally derived from the spice turmeric and was
combined with silk fibroin (SF) to improve its intracellular bioavailability. This study focused …

EPCO-31. Epigenomic intratumoral heterogeneity of glioblastoma in three-dimensional space

…, S Iyyanki, S Hilz, C Hong, J Phillips, S Chang… - Neuro …, 2020 - ncbi.nlm.nih.gov
Abstract Treatment failure in glioblastoma is often attributed to intratumoral heterogeneity (ITH),
which fosters tumor evolution and generation of therapy-resistant clones. While ITH in …

Epigenomic regulation and 3D Genome Structure in Muscle-Invasive Bladder Cancers

S Iyyanki - 2020 - etda.libraries.psu.edu
… The group first reported inactivating mutations in sister chromatid cohesion and segregation
process genes STAG2 and ESPL1, where the patient’s likelihood of survival was low with …

Abstract P39: Adipose-derived stem cell therapy to improve musculofascial healing in the irradiated abdominal wall

L Wang, TS Iyyanki, CD Branch-Brooks… - Plastic and …, 2013 - journals.lww.com
Abstract P39: ADIPOSE-DERIVED STEM CELL THERAPY TO IMPROVE
MUSCULOFASCIAL HEALING IN THE IRRADIATED ABDOMINAL WALL: Plastic and …

Nanoscale engineering of silk fibroin scaffold architecture to repair patient-specific cancer defects

LW Dunne, TS Iyyanki, CE Butler, AB Mathur - Nanotechnology in Cancer, 2017 - Elsevier
… Samples were tested with a 50 N load cell (Honeywell Sensotec, Columbus, OH, USA) at
a strain rate of 500 µm/s. Ultimate tensile strength (UTS), elastic modulus (E), and strain at …

Silk Fibroin-Decorin Engineered Biologics to Repair Musculofascial Defects

LW Dunne, N Falk, J Hubenak, TS Iyyanki… - … Medicine and Plastic …, 2019 - Springer
The use of synthetic mesh (eg, polypropylene [PP] mesh) and biologic (eg, porcine acellular
dermal matrix (PADM)) for the repair of abdominal wall musculofascial has limitations …