The Microarchitecture of C. elegans Behavior during Lethargus: Homeostatic Bout Dynamics, a Typical Body Posture, and Regulation by a Central Neuron
… with a homeostatic process (S) to regulate sleep-wake cycles. The process S represents an
… The time-course of S can be inferred from measurements of slow wave activity (SWA), ie, …
… The time-course of S can be inferred from measurements of slow wave activity (SWA), ie, …
[HTML][HTML] Serotonin-dependent kinetics of feeding bursts underlie a graded response to food availability in C. elegans
… of the environment and of the animal’s behaviour and characterize the distinct roles of …
along with the relative simplicity of the worm’s neuronal circuitry and anatomy, open the way …
along with the relative simplicity of the worm’s neuronal circuitry and anatomy, open the way …
[PDF][PDF] GIRK channel activation involves a local rearrangement of a preformed G protein channel complex
I Riven, S Iwanir, E Reuveny - Neuron, 2006 - cell.com
… Here, we show that the key activation entity, the Gbg complex, is closely associated with
the channel’s cytosolic domains at rest and that upon GPCR activation the Gbg dimer …
the channel’s cytosolic domains at rest and that upon GPCR activation the Gbg dimer …
Homeostasis in C. elegans sleep is characterized by two behaviorally and genetically distinct mechanisms
… of body posture at high temporal and spatial resolutions (Iwanir et al., 2013; Nagy et al.,
2014). Using this analysis and a 15 s weak light stimulus, we measured the durations of bouts of …
2014). Using this analysis and a 15 s weak light stimulus, we measured the durations of bouts of …
[PDF][PDF] Glia modulate a neuronal circuit for locomotion suppression during sleep in C. elegans
… Images were captured for 5 min at 4 frames/s and analyzed using a custom Java code for
AVE activity and position within the microfluidic device (see the Supplemental Experimental …
AVE activity and position within the microfluidic device (see the Supplemental Experimental …
[HTML][HTML] Serotonin promotes exploitation in complex environments by accelerating decision-making
Background Fast responses can provide a competitive advantage when resources are
inhomogeneously distributed. The nematode Caenorhabditis elegans was shown to modulate …
inhomogeneously distributed. The nematode Caenorhabditis elegans was shown to modulate …
Adrenaline-induced hyperpolarization of mouse pancreatic islet cells is mediated by G protein-gated inwardly rectifying potassium (GIRK) channels
S Iwanir, E Reuveny - Pflügers Archiv-European Journal of Physiology, 2008 - Springer
… 30 s at 94C, 30 s at 55C, 60 s at 72C] for 15 cycles and 10 min in 72C. RT-PCR product
locations (from CDS start) for the different gene products were: GIRK1, 435–1,100; GIRK2a, 914–…
locations (from CDS start) for the different gene products were: GIRK1, 435–1,100; GIRK2a, 914–…
[PDF][PDF] A memory circuit for coping with impending adversity
… during the 10 s after the switch and the mean activity during the 10 s prior to the switch (for
the AWC neurons), and the difference between the 20 s after the switch and the 20 s prior to …
the AWC neurons), and the difference between the 20 s after the switch and the 20 s prior to …
[HTML][HTML] Irrational behavior in C. elegans arises from asymmetric modulatory effects within single sensory neurons
… variance in worm’s preferences (RCI, BCI), we chose 46 different pairs of stimuli (consisted
of odorants, tastants, the buffer null option, and which span various magnitudes of CI’s), and …
of odorants, tastants, the buffer null option, and which span various magnitudes of CI’s), and …
Reduced activity of GIRK1‐containing heterotetramers is sufficient to affect neuronal functions, including synaptic plasticity and spatial learning and memory
… for up to 90 s. Each mouse was allowed to remain on the platform for 15 s and was then …
the platform within the 90 s, it was manually placed on the platform for 15 s. Memory was …
the platform within the 90 s, it was manually placed on the platform for 15 s. Memory was …