… As in the case of hemizygous deletion, silencing by DNA methylation may have affected
gene(s) other than RUNX3. To establish RUNX3 as causally related to gastric carcinogenesis, …

During carcinogenesis of pancreatic islets in transgenic mice, an angiogenic switch activates
the quiescent vasculature. Paradoxically, vascular endothelial growth factor (VEGF) and its …

Abstract Analysis of mice carrying mutant T-cell antigen receptor (TCP) genes indicates that
TCP-β gene rearrangement or expression is critical for the differentiation of CD4 − CD8 − …

IN mice γδ T-cell populations with distinct T-cell receptor (TCR) repertoires and homing
properties have been identified. Diversified populations are found in lymphoid organs 1–3 and …

Matrix metalloproteinases (MMPs) are essential for proper extracellular matrix remodeling.
We previously found that a membrane-anchored glycoprotein, RECK, negatively regulates …

… (q–s) The olfactory bulb of Line 5-1/R26-CFP mice, which received repeated administration
… + granule cells (red) were determined (r,s). Note that CFP labeling of granule cell dendrites …

Matrix proteolysis is thought to play a crucial role in several stages of tumor progression,
including angiogenesis, and the invasion and metastasis of tumor cells. We investigated the …

The immunobiology of Trypanosoma cruzi infection in mice is discussed under the following
headings: definition of the immunological problem; the experimental system; the …

… s) that may link Aβ amyloidosis and tauopathy. In any case, the advantages lie in the existence
of relevant negative controls and the lack of concern about overexpression artifact(s… (s) …

Loss-of-function mutations in human SCN1A gene encoding Na v 1.1 are associated with a
severe epileptic disorder known as severe myoclonic epilepsy in infancy. Here, we …