Over three decades have passed since the first report on the expression of CA125 by
ovarian tumors. Since that time our understanding of ovarian cancer biology has changed …

… Furthermore, treatment of the pituitaryderived MtT/S cell line with estrogen results in a
dosedependent increase in PAD expression and activity [42]. Together, these observations …

… For IHC, slides were incubated in DAB chromagen (Vector Labs) solutions according to
the manufacturer’s protocol, washed and then counterstained with Gill’s hematoxylin, and …

Background MUC16 is a cell surface mucin expressed at high levels by epithelial ovarian
tumors. Following proteolytic cleavage, cell surface MUC16 (csMUC16) is shed in the …

Background Cancer cells utilize a variety of mechanisms to evade immune detection and
attack. Effective immune detection largely relies on the formation of an immune synapse which …

Critical to the development of an effective HIV/AIDS model is the production of an animal
model that reproduces long-lasting active replication of HIV-1 followed by elicitation of virus-…

… The soft agar assay on the other hand is distinct from 2D culture systems because it quantifies
tumorigenicity by measuring a cell’s ability to proliferate and form colonies in suspension …

… network than it is to that of S. cerevisiae. Furthermore, among … with the proteomewide
interactome of S. cerevisiae, we are … by 4,989 S. pombe genes (corresponding to > 99% of all …

… Double-stranded breaks (DSBs) accompanied by PARP trapping strongly blocks
replication and induces S phase checkpoints, resulting in further DNA breaks and cytotoxicity, …

… generated the figure; Wabel E wrote the paclitaxel and bevacizumab resistance mechanism
and generated the figure; Mitchell K wrote the platinum resistance mechanisms; Horibata S …