[PDF][PDF] Mouse hematopoietic stem cells

GJ Spangrude, L Smith, N Uchida, K Ikuta, S Heimfeld… - Blood, 1991 - researchgate.net
… In our experiments, CFU-S and CFU-T activities were present together in a single
population, the Thy-l'"Lin"'gSca-l' subset.*" Within reasonable error, it turned out that the Thy-…

Hematopoietic SCT with cryopreserved grafts: adverse reactions after transplantation and cryoprotectant removal before infusion

Z Shu, S Heimfeld, D Gao - Bone marrow transplantation, 2014 - nature.com
… ’s lymphoma compared with non-Hodgkin’s lymphoma or multiple myeloma 8 ) or the
type of prior treatments given and chemotherapeutic agents received, 15 as can the infusion …

Systematic localization of common disease-associated variation in regulatory DNA

…, D Bates, RS Hansen, S Neph, PJ Sabo, S Heimfeld… - Science, 2012 - science.org
… of pathogenic cell types for Crohn’s disease, multiple sclerosis, and … Although Crohn’s
pathology has classically been associated … any prior knowledge about Crohn’s disease pathology. …

HLA-identical stem cell transplantation: is there an optimal CD34 cell dose?

S Heimfeld - Bone marrow transplantation, 2003 - nature.com
A review of the published literature, supplemented with a recent analysis of Fred Hutchinson
data, has been undertaken to investigate the association of infused CD34 cell dose with …

[HTML][HTML] CD19 CAR–T cells of defined CD4+:CD8+ composition in adult B cell ALL patients

…, B Wood, D Li, J Cao, S Heimfeld… - The Journal of …, 2016 - Am Soc Clin Investig
… The eligibility criteria for this study did not exclude any patient based on the absolute
lymphocyte count or on a predetermined measurement of the ability of the patient’s T cells to …

[HTML][HTML] Transplantation of bone marrow as compared with peripheral-blood cells from HLA-identical relatives in patients with hematologic cancers

…, R Storb, K Blume, S Heimfeld, S Rowley… - … England Journal of …, 2001 - Mass Medical Soc
Background In recipients of allogeneic hematopoietic-cell transplants, peripheral-blood
cells mobilized with the use of filgrastim (recombinant granulocyte colony-stimulating factor) …

Immunotherapy of non-Hodgkin's lymphoma with a defined ratio of CD8+ and CD4+ CD19-specific chimeric antigen receptor–modified T cells

…, X Chen, L Soma, B Wood, D Li, S Heimfeld… - Science translational …, 2016 - science.org
… , results of therapy in refractory non-Hodgkin’s lymphoma (NHL) have been less impressive
(… %, depending on the status of the patient’s disease at the time the T cells were collected (15)…

[HTML][HTML] Myeloablative autologous stem-cell transplantation for severe scleroderma

…, S Heimfeld, C Hosing, S Forman… - … England Journal of …, 2018 - Mass Medical Soc
Background Despite current therapies, diffuse cutaneous systemic sclerosis (scleroderma)
often has a devastating outcome. We compared myeloablative CD34+ selected autologous …

[HTML][HTML] Durable molecular remissions in chronic lymphocytic leukemia treated with CD19-specific chimeric antigen receptor–modified T cells after failure of ibrutinib

…, B Wood, A Lozanski, JC Byrd, S Heimfeld… - Journal of Clinical …, 2017 - ncbi.nlm.nih.gov
Purpose We evaluated the safety and feasibility of anti-CD19 chimeric antigen receptor–modified
T (CAR-T) cell therapy in patients with chronic lymphocytic leukemia (CLL) who had …

CD34+ hematopoietic stem-progenitor cell microRNA expression and function: a circuit diagram of differentiation control

…, S Morisot, J Alder, C Liu, S Heimfeld… - Proceedings of the …, 2007 - National Acad Sciences
MicroRNAs (miRNAs) are a recently identified class of epigenetic elements consisting of
small noncoding RNAs that bind to the 3′ untranslated region of mRNAs and down-regulate …