User profiles for S. Hautaniemi
Sampsa HautaniemiProfessor of systems biology, Faculty of Medicine, University of Helsinki Verified email at helsinki.fi Cited by 12099 |
Impact of DNA amplification on gene expression patterns in breast cancer
…, P Kauraniemi, S Hautaniemi, M Wolf, S Mousses… - Cancer research, 2002 - AACR
… A database of genomic sequence alignment information for mRNA sequences was
created from the August 2001 freeze of the University of California Santa Cruz’s GoldenPath …
created from the August 2001 freeze of the University of California Santa Cruz’s GoldenPath …
PINA v2. 0: mining interactome modules
The Protein Interaction Network Analysis (PINA) platform is a comprehensive web resource,
which includes a database of unified protein–protein interaction data integrated from six …
which includes a database of unified protein–protein interaction data integrated from six …
Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks
A Wolf-Yadlin, S Hautaniemi… - Proceedings of the …, 2007 - National Acad Sciences
Although recent developments in MS have enabled the identification and quantification of
hundreds of phosphorylation sites from a given biological sample, phosphoproteome analysis …
hundreds of phosphorylation sites from a given biological sample, phosphoproteome analysis …
Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer
…, S Nordling, O Kallioniemi, S Hautaniemi… - The EMBO …, 2011 - embopress.org
High androgen receptor (AR) level in primary tumour predicts increased prostate cancer‐specific
mortality. However, the mechanisms that regulate AR function in prostate cancer are …
mortality. However, the mechanisms that regulate AR function in prostate cancer are …
[HTML][HTML] Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues
…, H Edgren, M Wolf, J Astola, M Nees, S Hautaniemi… - Genome biology, 2008 - Springer
Our knowledge on tissue- and disease-specific functions of human genes is rather limited
and highly context-specific. Here, we have developed a method for the comparison of mRNA …
and highly context-specific. Here, we have developed a method for the comparison of mRNA …
Integrated network analysis platform for protein-protein interactions
There is an increasing demand for network analysis of protein-protein interactions (PPIs).
We introduce a web-based protein interaction network analysis platform (PINA), which …
We introduce a web-based protein interaction network analysis platform (PINA), which …
Longitudinal single-cell RNA-seq analysis reveals stress-promoted chemoresistance in metastatic ovarian cancer
…, J Hynninen, A Virtanen, A Häkkinen, S Hautaniemi… - Science …, 2022 - science.org
… Funding: This work was supported by the European Union’s Horizon 2020 research and
innovation programme under grant agreement no. 667403 for HERCULES (Comprehensive …
innovation programme under grant agreement no. 667403 for HERCULES (Comprehensive …
[HTML][HTML] Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance
…, S Grénman, R Lehtonen, S Hautaniemi… - Nature …, 2021 - nature.com
Due to its dynamic nature, the evolution of cancer cell-extracellular matrix (ECM) crosstalk,
critically affecting metastasis and treatment resistance, remains elusive. Our results show that …
critically affecting metastasis and treatment resistance, remains elusive. Our results show that …
[HTML][HTML] Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer
Combined PARP and immune checkpoint inhibition has yielded encouraging results in
ovarian cancer, but predictive biomarkers are lacking. We performed immunogenomic profiling …
ovarian cancer, but predictive biomarkers are lacking. We performed immunogenomic profiling …
FoxA1 specifies unique androgen and glucocorticoid receptor binding events in prostate cancer cells
… Further studies are needed to elucidate the mechanism(s) by which the partial antiandrogenic
action of Dex is elicited; intriguingly, it does not appear to involve direct competition …
action of Dex is elicited; intriguingly, it does not appear to involve direct competition …