… Gerecht's laboratory at Johns Hopkins University. The physical properties of the biosynthetic
dextran scaffold can be tuned to facilitate cell infiltration and scaffold degradation by …

A growing number of failing clinical trials for cancer therapy are substantiating the need to
upgrade the current practice in culturing tumor cells and modeling tumor angiogenesis in vitro. …

… In vivo vascular permeability ranges from 10 −6 to 10 −7 cm s −… values as low as 10 −6 cm
s −1 for BSA and 70 kDa dextran (… Lower permeability values for BSA (about 10 −7 cm s −1 ) …

Control of self-renewal and differentiation of human ES cells (hESCs) remains a challenge.
This is largely due to the use of culture systems that involve poorly defined animal products …

… To investigate angiogenesis within the wound, we used Masson’s trichrome staining, which
revealed an increase in delineated vascular networks and the formation of a collagen layer …

We propose a new methodology to enhance the vascular differentiation of human embryonic
stem cells (hESCs) by encapsulation in a bioactive hydrogel. hESCs were encapsulated in …

We report that human embryonic stem cells contain a population of vascular progenitor cells
that have the ability to differentiate into endothelial-like and smooth muscle (SM)-like cells. …

… , titanium), length of stimulus (1 and 90 s) and age of EBs at the onset of electrical stimulation
(4 … for stainless steel electrodes, for signal duration of 90 s and for 4-day-old EBs. Notably, …

… Although endothelial cells (ECs), which compose the vasculature’s inner lining, are
intrinsically able to form nascent networks, these structures regress without the recruitment of …

Objective: To test the hypothesis that human embryonic stem cells (hESCs) can be guided
to form new myocardium by transplantation into the normal or infarcted heart, and to assess …