User profiles for S. Gandhi

Sumit G. Gandhi

- Verified email at iiim.ac.in - Cited by 3085

Sacha E Gandhi

- Verified email at nhs.net - Cited by 397

[HTML][HTML] Mechanism of oxidative stress in neurodegeneration

S Gandhi, AY Abramov - Oxidative medicine and cellular longevity, 2012 - hindawi.com
… neurodegenerative diseases, Alzheimer’s disease (AD), and Parkinson’s disease (PD). Most
… disorders, including Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and …

Understanding the molecular causes of Parkinson's disease

A Wood-Kaczmar, S Gandhi, NW Wood - Trends in molecular medicine, 2006 - cell.com
Parkinson's disease (PD) is a neurodegenerative disease that is both common and incurable.
The majority of cases are sporadic and of unknown origin but several genes have been …

Surgery for epilepsy

S West, SJ Nevitt, J Cotton, S Gandhi… - Cochrane Database …, 2019 - cochranelibrary.com
Objectives The primary objective is to assess the overall outcome of epilepsy surgery
according to evidence from randomised controlled trials.

Preexisting and de novo humoral immunity to SARS-CoV-2 in humans

…, LR Wedderburn, R Beale, C Swanton, S Gandhi… - Science, 2020 - science.org
… SARS-CoV-2 spike glycoprotein (S)–reactive antibodies … titers of SARS-CoV-2 S–reactive
IgG antibodies targeting both … and SARS-CoV-2 S pseudotypes. Distinguishing preexisting and …

Neutralising antibody activity against SARS-CoV-2 VOCs B. 1.617. 2 and B. 1.351 by BNT162b2 vaccination

…, G Kassiotis, V Libri, B Williams, C Swanton, S Gandhi… - The Lancet, 2021 - thelancet.com
… inferring vaccine efficacy against B.1.617.2 in the UK based on rates of S-gene target failure
during quantitative RT-PCR testing. With increasing case numbers and the proportion of …

A common LRRK2 mutation in idiopathic Parkinson's disease

WP Gilks, PM Abou-Sleiman, S Gandhi, S Jain… - The Lancet, 2005 - thelancet.com
… WP Gilks, P Abou-Sleiman, and S Jain did the molecular analysis and collection of results.
Clinical and pathological review of patients with the mutation was by J Lynch and S Gandhi. P …

[HTML][HTML] Epidemiology, clinical profile, management, and outcome of COVID-19-associated rhino-orbital-cerebral mucormycosis in 2826 patients in India …

…, S Shah, S Shah, S Dubey, S Gandhi… - Indian journal of …, 2021 - journals.lww.com
… (ROCM) has reached epidemic proportion during India’s second wave of COVID-19 pandemic,
… The Chi-square and Fisher’s exact tests were used to compare outcomes. For all tests, p …

[PDF][PDF] PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death

S Gandhi, A Wood-Kaczmar, Z Yao, H Plun-Favreau… - Molecular cell, 2009 - cell.com
Mutations in PINK1 cause autosomal recessive Parkinson's disease. PINK1 is a mitochondrial
kinase of unknown function. We investigated calcium homeostasis and mitochondrial …

[HTML][HTML] The pathogenesis of acute pulmonary edema associated with hypertension

SK Gandhi, JC Powers, AM Nomeir… - … England Journal of …, 2001 - Mass Medical Soc
Background Patients with acute pulmonary edema often have marked hypertension but,
after reduction of the blood pressure, have a normal left ventricular ejection fraction (≥0.50). …

Heterochromatic Silencing and HP1 Localization in Drosophila Are Dependent on the RNAi Machinery

M Pal-Bhadra, BA Leibovitch, SG Gandhi, M Rao… - Science, 2004 - science.org
… (8) have reported a loss of H3-mK9 and Swi6, the HP1 homolog, at centromeric repeats
in S. pombe as a result of mutations in the RNAi system. We examined the effects of …