A concise guide to cDNA microarray analysis

P Hegde, R Qi, K Abernathy, C Gay, S Dharap… - …, 2000 - Future Science
Microarray expression analysis has become one of the most widely used functional
genomics tools. Efficient application of this technique requires the development of robust and …

Molecular targeting of drug delivery systems to cancer

T Minko, SS Dharap, RI Pakunlu… - Current drug targets, 2004 - ingentaconnect.com
… Therefore a possibility exists that vector virus will replicate and the suicide gene(s) will be …
To determine the expression of the gene encoding LHRH receptor (LHRHR), Dharap and …

Tumor-specific targeting of an anticancer drug delivery system by LHRH peptide

SS Dharap, Y Wang, P Chandna… - Proceedings of the …, 2005 - National Acad Sciences
The central problem in cancer chemotherapy is the severe toxic side effects of anticancer
drugs on healthy tissues. Invariably the side effects impose dose reduction, treatment delay, or …

Molecular targeting of drug delivery systems to ovarian cancer by BH3 and LHRH peptides

SS Dharap, B Qiu, GC Williams, P Sinko, S Stein… - Journal of controlled …, 2003 - Elsevier
Novel targeted proapoptotic anticancer drug delivery systems were developed and evaluated.
Poly(ethyleneglycol) (PEG) conjugates were used as carriers. Camptothecin (CPT) was …

Utility of optic nerve ultrasonography in head injury

RS Goel, NK Goyal, SB Dharap, M Kumar, MA Gore - Injury, 2008 - Elsevier
BACKGROUND: CT has evolved as the gold standard for evaluation of head injury, but early
CT is not always possible. Bedside ultrasonography is available in most trauma units and …

Antitumor activity of poly (ethylene glycol)–camptothecin conjugate: The inhibition of tumor growth in vivo

D Yu, P Peng, SS Dharap, Y Wang, M Mehlig… - Journal of Controlled …, 2005 - Elsevier
Antitumor effect of poly(ethylene glycol)–camptothecin conjugate (PEG–CPT) was studied
in the nude mouse model of human colon cancer xenografts. The animals were treated …

Implementation of the World Health Organization trauma care checklist program in 11 centers across multiple economic strata: effect on care process measures

…, C Bloem, W Chadbunchachai, S Dharap… - World journal of …, 2017 - Wiley Online Library
… Outcome data were identified through chart review; any inconsistencies found were resolved
by the patient’s healthcare providers. Injury severity was quantified using injury severity …

Targeted proapoptotic LHRH-BH3 peptide

SS Dharap, T Minko - Pharmaceutical research, 2003 - Springer
Purpose. The purpose of this work was to construct and evaluate a novel targeted proapoptotic
peptide for cancer treatment. Methods. The peptide consisted of luteinizing hormone-…

[PDF][PDF] Incidence and risk factors of postoperative complications in general surgery patients

SB Dharap, P Barbaniya, S Navgale, PS Barbaniya Sr… - Cureus, 2022 - cureus.com
Background Postoperative complications, which are undesirable consequences of surgery,
need to be minimized to ensure the quality of surgical care. In this study, we aimed to …

Identification of tumor markers in models of human colorectal cancer using a 19,200-element complementary DNA microarray

P Hegde, R Qi, R Gaspard, K Abernathy, S Dharap… - Cancer Research, 2001 - AACR
… Images were analyzed to determine each spot’s background-subtracted integrated fluorescence
intensity in both the Cy3 and Cy5 channels using TIGR Spotfinder. This software uses a …