[HTML][HTML] Polyphenols targeting MAPK mediated oxidative stress and inflammation in rheumatoid arthritis
T Behl, T Upadhyay, S Singh, S Chigurupati… - Molecules, 2021 - mdpi.com
… Hypoxia is a phenomenon found in RA joints that has been attributed to the inflammation
reaction’s quick cell multiplication; in any case, considering the literature data, hypoxia …
reaction’s quick cell multiplication; in any case, considering the literature data, hypoxia …
[HTML][HTML] Vasculoprotective effects of pomegranate (Punica granatum L.)
Pomegranate (Punica granatum L.), one of the oldest known edible fruits, is nowadays
broadly consumed throughout the world. Its fruits and seeds as well as other anatomical …
broadly consumed throughout the world. Its fruits and seeds as well as other anatomical …
[HTML][HTML] Targeting probiotics in rheumatoid arthritis
…, S Singh, S Chigurupati, S Vijayabalan, S Das… - Nutrients, 2021 - mdpi.com
… qualities, if appropriate, must also be assessed, as must the strain’s physiological and
genetic stability throughout the product’s shelf life and at the functional center in its host [53]. …
genetic stability throughout the product’s shelf life and at the functional center in its host [53]. …
Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits
The innate immune system senses the invasion of pathogenic microorganisms and tissue
injury through Toll-like receptors (TLR), a mechanism thought to be limited to immune cells. …
injury through Toll-like receptors (TLR), a mechanism thought to be limited to immune cells. …
Effects of cerium oxide nanoparticles on the growth of keratinocytes, fibroblasts and vascular endothelial cells in cutaneous wound healing
Rapid and effective wound healing requires a coordinated cellular response involving
fibroblasts, keratinocytes and vascular endothelial cells (VECs). Impaired wound healing can …
fibroblasts, keratinocytes and vascular endothelial cells (VECs). Impaired wound healing can …
Acute kidney injury leads to inflammation and functional changes in the brain
M Liu, Y Liang, S Chigurupati, JD Lathia… - Journal of the …, 2008 - journals.lww.com
Although neurologic sequelae of acute kidney injury (AKI) are well described, the pathogenesis
of acute uremic encephalopathy is poorly understood. This study examined the short-…
of acute uremic encephalopathy is poorly understood. This study examined the short-…
Gamma secretase–mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke
Mice transgenic for antisense Notch and normal mice treated with inhibitors of the Notch-activating
enzyme γ-secretase showed reduced damage to brain cells and improved functional …
enzyme γ-secretase showed reduced damage to brain cells and improved functional …
Intravenous immunoglobulin (IVIG) protects the brain against experimental stroke by preventing complement-mediated neuronal cell death
…, A Cheng, MR Mughal, S Chigurupati… - Proceedings of the …, 2007 - National Acad Sciences
… Author contributions: TVA and S.-CT and MB and MPM contributed equally to this work;
MB and MPM designed research; TVA, S.-CT, JDL, AC, MRM, SC, TM, SLC, D.-GJ, XO, DNG, …
MB and MPM designed research; TVA, S.-CT, JDL, AC, MRM, SC, TM, SLC, D.-GJ, XO, DNG, …
TP53 copy number expansion is associated with the evolution of increased body size and an enhanced DNA damage response in elephants
… This lack of correlation is often referred to as ’Peto’s Paradox’. Here, we show that the elephant
… evolution of very large body sizes and the resolution of Peto’s paradox in Proboscideans. …
… evolution of very large body sizes and the resolution of Peto’s paradox in Proboscideans. …
Receptor channel TRPC6 is a key mediator of Notch-driven glioblastoma growth and invasiveness
S Chigurupati, R Venkataraman, D Barrera… - Cancer research, 2010 - AACR
… The molecular signal(s) that links tissue hypoxia to tumor aggressiveness is poorly … and
because Ca 2+ signaling promotes G 1 -S phase transition and cell cycle progression in a variety …
because Ca 2+ signaling promotes G 1 -S phase transition and cell cycle progression in a variety …