User profiles for S. Chigurupati

Srinivasulu Chigurupati

- Verified email at fda.hhs.gov - Cited by 4529

Dr.Sridevi Chigurupati

- Verified email at qu.edu.sa - Cited by 3148

[HTML][HTML] Polyphenols targeting MAPK mediated oxidative stress and inflammation in rheumatoid arthritis

T Behl, T Upadhyay, S Singh, S Chigurupati… - Molecules, 2021 - mdpi.com
… Hypoxia is a phenomenon found in RA joints that has been attributed to the inflammation
reaction’s quick cell multiplication; in any case, considering the literature data, hypoxia …

[HTML][HTML] Vasculoprotective effects of pomegranate (Punica granatum L.)

…, C Özen, IM Abu-Reidah, S Chigurupati… - Frontiers in …, 2018 - frontiersin.org
Pomegranate (Punica granatum L.), one of the oldest known edible fruits, is nowadays
broadly consumed throughout the world. Its fruits and seeds as well as other anatomical …

[HTML][HTML] Targeting probiotics in rheumatoid arthritis

…, S Singh, S Chigurupati, S Vijayabalan, S Das… - Nutrients, 2021 - mdpi.com
… qualities, if appropriate, must also be assessed, as must the strain’s physiological and
genetic stability throughout the product’s shelf life and at the functional center in its host [53]. …

Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits

…, JD Lathia, DA Siler, S Chigurupati… - Proceedings of the …, 2007 - National Acad Sciences
The innate immune system senses the invasion of pathogenic microorganisms and tissue
injury through Toll-like receptors (TLR), a mechanism thought to be limited to immune cells. …

Effects of cerium oxide nanoparticles on the growth of keratinocytes, fibroblasts and vascular endothelial cells in cutaneous wound healing

S Chigurupati, MR Mughal, E Okun, S Das, A Kumar… - Biomaterials, 2013 - Elsevier
Rapid and effective wound healing requires a coordinated cellular response involving
fibroblasts, keratinocytes and vascular endothelial cells (VECs). Impaired wound healing can …

Acute kidney injury leads to inflammation and functional changes in the brain

M Liu, Y Liang, S Chigurupati, JD Lathia… - Journal of the …, 2008 - journals.lww.com
Although neurologic sequelae of acute kidney injury (AKI) are well described, the pathogenesis
of acute uremic encephalopathy is poorly understood. This study examined the short-…

Gamma secretase–mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke

…, M Gleichmann, E Okun, VD Dixit, S Chigurupati… - Nature medicine, 2006 - nature.com
Mice transgenic for antisense Notch and normal mice treated with inhibitors of the Notch-activating
enzyme γ-secretase showed reduced damage to brain cells and improved functional …

Intravenous immunoglobulin (IVIG) protects the brain against experimental stroke by preventing complement-mediated neuronal cell death

…, A Cheng, MR Mughal, S Chigurupati… - Proceedings of the …, 2007 - National Acad Sciences
… Author contributions: TVA and S.-CT and MB and MPM contributed equally to this work;
MB and MPM designed research; TVA, S.-CT, JDL, AC, MRM, SC, TM, SLC, D.-GJ, XO, DNG, …

TP53 copy number expansion is associated with the evolution of increased body size and an enhanced DNA damage response in elephants

M Sulak, L Fong, K Mika, S Chigurupati, L Yon… - elife, 2016 - elifesciences.org
… This lack of correlation is often referred to as ’Peto’s Paradox’. Here, we show that the elephant
… evolution of very large body sizes and the resolution of Peto’s paradox in Proboscideans. …

Receptor channel TRPC6 is a key mediator of Notch-driven glioblastoma growth and invasiveness

S Chigurupati, R Venkataraman, D Barrera… - Cancer research, 2010 - AACR
… The molecular signal(s) that links tissue hypoxia to tumor aggressiveness is poorly … and
because Ca 2+ signaling promotes G 1 -S phase transition and cell cycle progression in a variety …