A variety of animals have been used for tuberculosis research, and each animal model has
its strengths and weaknesses. We sought to develop a non-human primate model of …

Nonhuman primates were used to develop an animal model that closely mimics human
Mycobacterium tuberculosis infection. Cynomolgus macaques were infected with low doses of …

Infection with Asian-lineage Zika virus (ZIKV) has been associated with Guillain–Barré
syndrome and fetal abnormalities, but the underlying mechanisms remain poorly understood. …

We previously described that low-dose Mycobacterium tuberculosis infection in cynomolgus
macaques results in a spectrum of disease similar to that of human infection: primary …

Context: Fine-needle aspiration cytology (FNAC) is the gold standard for the differential
diagnosis of thyroid nodules but has the limitation of inadequate sampling or indeterminate …

Little is known regarding the early events of infection of humans with Mycobacterium tuberculosis.
The cynomolgus macaque is a useful model of tuberculosis, with strong similarities to …

Recent human decedent model studies 1 , 2 and compassionate xenograft use 3 have explored
the promise of porcine organs for human transplantation. To proceed to human studies, …

“Elite controllers” are individuals that durably control human immunodeficiency virus or
simian immunodeficiency virus replication without therapeutic intervention. The study of these …

Objective An increased risk of tuberculosis has been documented in humans treated with
tumor necrosis factor α (TNFα)–neutralizing agents. In murine models, impaired signaling by …

Infection with Zika virus (ZIKV) is associated with human congenital fetal anomalies. To
model fetal outcomes in nonhuman primates, we administered Asian-lineage ZIKV …