Inactivating mutations in the BCKDK gene, which codes for the kinase responsible for the
negative regulation of the branched‐chain α‐keto acid dehydrogenase complex ( BCKD ), …

… Ethics approval for this study was obtained from the St Thomas’s local research ethics
committee. This research followed the tenets of the Declaration of Helsinki. A patient information …

The emergence of next generation DNA sequencing technology is enabling high-resolution
cancer genome analysis. Large-scale projects like the International Cancer Genome …

… To our knowledge, this is the only study investigating the pretreatment TOF (measured with
electronic Shiøtz tonography) and IOP as determinants of success 12 month’s post-360 SLT …

… The shunt was inserted according to the manufacturer’s directions. The scleral flap was then
closed with 3 interrupted 10-0 nylon sutures, 2 at the base near the limbus and 1 at the apex…

… ALT is usually performed using 50–100 applications of a 50 μm spot size, 0.1 s duration
and average power setting of between 400 and 1000 mW. It is a relatively high energy level …

… The inner wall of Schlemm’s canal marks the outer border of the juxtacanalicular meshwork
which serves as the major source of aqueous humor outflow resistance. The extracellular …

… In order to explore this, we made some calculations using the Goldmann’s equation (see
online Supplementary appendix). If we assume that other aspects of aqueous dynamic …

… The ‘R’ values of the curve at every 30 s time point were manually entered into the McLaren
tonography computer program. This program fits a second-degree polynomial by the least …

Purpose.: To compare the baseline aqueous humor dynamics in white Caucasians and
patients of African origin with previously untreated primary open-angle glaucoma (POAG) or …