User profiles for S. W. Cheetham

Seth Cheetham

University of Queensland
Verified email at uq.edu.au
Cited by 1788

[HTML][HTML] Long noncoding RNAs and the genetics of cancer

SW Cheetham, F Gruhl, JS Mattick… - British journal of cancer, 2013 - nature.com
Cancer is a disease of aberrant gene expression. While the genetic causes of cancer have
been intensively studied, it is becoming evident that a large proportion of cancer susceptibility …

Overcoming challenges and dogmas to understand the functions of pseudogenes

SW Cheetham, GJ Faulkner, ME Dinger - Nature Reviews Genetics, 2020 - nature.com
Pseudogenes are defined as regions of the genome that contain defective copies of genes.
They exist across almost all forms of life, and in mammalian genomes are annotated in …

Vasculature organotropism in drug delivery

A Amruta, D Iannotta, SW Cheetham, T Lammers… - Advanced Drug Delivery …, 2023 - Elsevier
Over the past decades, there has been an exponential increase in the development of
preclinical and clinical nanodelivery systems, and recently, an accelerating demand to deliver …

[PDF][PDF] Nanopore sequencing enables comprehensive transposable element epigenomic profiling

…, J Faivre, PM Brennan, SR Richardson, SW Cheetham… - Molecular Cell, 2020 - cell.com
Transposable elements (TEs) drive genome evolution and are a notable source of
pathogenesis, including cancer. While CpG methylation regulates TE activity, the locus-specific …

Cell-type-specific profiling of protein–DNA interactions without cell isolation using targeted DamID with next-generation sequencing

OJ Marshall, TD Southall, SW Cheetham, AH Brand - Nature protocols, 2016 - nature.com
Cheetham, W. Gruhn, A. Surani and AHB, data not shown). … Owen J Marshall, Tony D
Southall, Seth W Cheetham & Andrea H Brand … Seth W Cheetham

[HTML][HTML] LINE-1 evasion of epigenetic repression in humans

…, RL Troskie, JS Jesuadian, SW Cheetham… - Molecular cell, 2019 - cell.com
Epigenetic silencing defends against LINE-1 (L1) retrotransposition in mammalian cells.
However, the mechanisms that repress young L1 families and how L1 escapes to cause …

[HTML][HTML] mRNA vaccine quality analysis using RNA sequencing

…, E Ariens, JR Peters, T Wong, SW Cheetham… - Nature …, 2023 - nature.com
The success of mRNA vaccines has been realised, in part, by advances in manufacturing
that enabled billions of doses to be produced at sufficient quality and safety. However, mRNA …

Pinstripe: a suite of programs for integrating transcriptomic and proteomic datasets identifies novel proteins and improves differentiation of protein-coding and non …

DK Gascoigne, SW Cheetham, PB Cattenoz… - …, 2012 - academic.oup.com
Motivation: Comparing transcriptomic data with proteomic data to identify protein-coding
sequences is a long-standing challenge in molecular biology, one that is exacerbated by the …

Methylartist: tools for visualizing modified bases from nanopore sequence data

SW Cheetham, M Kindlova, AD Ewing - Bioinformatics, 2022 - academic.oup.com
… Seth W CheethamCheetham and Michaela Kindlova should be regarded as Joint
First Authors. … Cheetham and Michaela Kindlova should be regarded as Joint First Authors. …

[HTML][HTML] Long-read cDNA sequencing identifies functional pseudogenes in the human transcriptome

…, TR Mercer, AD Ewing, GJ Faulkner, SW Cheetham - Genome biology, 2021 - Springer
Pseudogenes are gene copies presumed to mainly be functionless relics of evolution due to
acquired deleterious mutations or transcriptional silencing. Using deep full-length PacBio …