User profiles for S. R. Doyle

Stephen Doyle

Group Leader & UKRI Future Leaders Fellow, Wellcome Sanger Institute
Verified email at sanger.ac.uk
Cited by 2130

[HTML][HTML] Refugia and anthelmintic resistance: concepts and challenges

…, NJ Beesley, C Britton, U Chaudhry, SR Doyle… - International Journal for …, 2019 - Elsevier
Anthelmintic resistance is a threat to global food security. In order to alleviate the selection
pressure for resistance and maintain drug efficacy, management strategies increasingly aim …

[HTML][HTML] Challenges and opportunities for the adoption of molecular diagnostics for anthelmintic resistance

AC Kotze, JS Gilleard, SR Doyle, RK Prichard - International Journal for …, 2020 - Elsevier
Anthelmintic resistance is a significant threat to livestock production systems worldwide and
is emerging as an important issue in companion animal parasite management. It is also an …

Genome-wide approaches to investigate anthelmintic resistance

SR Doyle, JA Cotton - Trends in parasitology, 2019 - cell.com
The rapid evolution of anthelmintic resistance in a number of parasites of livestock and
domesticated animals has occurred in response to widespread use of anthelmintics for parasite …

Concurrent validity of the Alcohol Use Disorders Identification Test (AUDIT) and AUDIT zones in defining levels of severity among out‐patients with alcohol …

DM Donovan, DR Kivlahan, SR Doyle… - …, 2006 - Wiley Online Library
Aims To examine among alcohol‐dependent out‐patient clients the concurrent validity of the
Alcohol Use Disorders Identification Test (AUDIT) total score and ‘zones’ suggested by the …

Opioid use behaviors, mental health and pain—development of a typology of chronic pain patients

CJ Banta-Green, JO Merrill, SR Doyle… - Drug and alcohol …, 2009 - Elsevier
BACKGROUND: The intersection of pain, addiction and mental health has not been
adequately described. We describe the roles of these three conditions in a chronic pain patient …

[PDF][PDF] Genomic landscape of drug response reveals mediators of anthelmintic resistance

SR Doyle, R Laing, D Bartley, A Morrison, N Holroyd… - Cell Reports, 2022 - cell.com
Like other pathogens, parasitic helminths can rapidly evolve resistance to drug treatment.
Understanding the genetic basis of anthelmintic drug resistance in parasitic nematodes is key …

[HTML][HTML] The genome of Onchocerca volvulus, agent of river blindness

…, A Grote, B Harsha, A Tracey, R Beech, SR Doyle… - Nature …, 2016 - nature.com
Human onchocerciasis is a serious neglected tropical disease caused by the filarial nematode
Onchocerca volvulus that can lead to blindness and chronic disability. Control of the …

The factor structure of the alcohol use disorders identification test (AUDIT)

SR Doyle, DM Donovan, DR Kivlahan - Journal of Studies on Alcohol and …, 2007 - jsad.com
Doyle at the above address or via email at: srdoyle@u.washington.edu. Dennis M. Donovan
is also with the Department of Psychiatry and Behavioral Sciences, University of Washington…

[HTML][HTML] Genomic and transcriptomic variation defines the chromosome-scale assembly of Haemonchus contortus, a model gastrointestinal worm

SR Doyle, A Tracey, R Laing, N Holroyd… - Communications …, 2020 - nature.com
Haemonchus contortus is a globally distributed and economically important gastrointestinal
pathogen of small ruminants and has become a key nematode model for studying …

[HTML][HTML] Biology and genome of a newly discovered sibling species of Caenorhabditis elegans

…, R Kumagai, A Tracey, N Holroyd, SR Doyle… - Nature …, 2018 - nature.com
A ‘sibling’ species of the model organism Caenorhabditis elegans has long been sought for
use in comparative analyses that would enable deep evolutionary interpretations of …