[HTML][HTML] Parkin cooperates with GDNF/RET signaling to prevent dopaminergic neuron degeneration

…, B Mohammadi, E Motori, SK Ponna… - The Journal of …, 2015 - Am Soc Clin Investig
Parkin and the glial cell line–derived neurotrophic factor (GDNF) receptor RET have both
been independently linked to the dopaminergic neuron degeneration that underlies Parkinson’…

CHCHD10 mutations p.R15L and p.G66V cause motoneuron disease by haploinsufficiency

…, P Oeckl, K Müller, SK Ponna… - Human molecular …, 2018 - academic.oup.com
Mutations in the mitochondrially located protein CHCHD10 cause motoneuron disease by
an unknown mechanism. In this study, we investigate the mutations p.R15L and p.G66V in …

Structural basis for PDZ domain interactions in the post‐synaptic density scaffolding protein Shank3

SK Ponna, S Ruskamo, M Myllykoski… - Journal of …, 2018 - Wiley Online Library
The Shank proteins are crucial scaffolding elements of the post‐synaptic density ( PSD ).
One of the best‐characterized domains in Shank is the PDZ domain, which binds to C‐terminal …

Structure of an unconventional SH3 domain from the postsynaptic density protein Shank3 at ultrahigh resolution

SK Ponna, M Myllykoski, TM Boeckers… - … and biophysical research …, 2017 - Elsevier
The Shank family comprises three large multi-domain proteins playing central roles as protein
scaffolds in the neuronal postsynaptic density. The Shank proteins are closely linked to …

[PDF][PDF] Determination of simvastatin and diltiazem in rat plasma by HPLC and pharmacokinetic studies

V Eggadi, SK Ponna, SR Kankanala… - Int J Pharm Sci …, 2013 - academia.edu
To develop a simple and sensitive high performance liquid chromatographic method for the
simultaneous estimation of Simvastatin (SIMVA) and Diltiazem (DTZ) in rat plasma and also …

Sub-atomic resolution X-ray diffraction of the SH3 domain from the post-synaptic density protein Shank3

SK Ponna, M Myllykoski, TM Boeckers, P Kursula - BioRxiv, 2016 - biorxiv.org
The post-synaptic density multidomain scaffolding proteins of the Shank family are
structurally poorly characterised. The Shank family consists of three members, and domain-specific …

Influence of Heat Generation and Thermal Radiation on MHD Flow in a Vertical Micro-Porous-Channel in the Presence of Viscous Dissipation

B Ponna, V Malapati - Mapana Journal of Sciences, 2021 - search.proquest.com
This article analyses the influence of heat generation and thermal radiation on steady
hydromagnetic fully developed natural convection flow in a vertical micro-porous–channel in the …

[HTML][HTML] Crystallographic home-source X-ray data for the atomic-resolution experimental phasing of the Shank3 SH3 domain structure from pseudomerohedrally …

SK Ponna, M Myllykoski, P Kursula - Data in brief, 2018 - Elsevier
By far most macromolecular crystallographic data collection and experimental phasing is
nowadays carried out using synchrotron radiation. Here, we present two crystallographic …

Role of TRIM31 in the pathogenesis of esophageal adenocarcinoma

MS Hassan, J Mast, A Ritter, S Ponna, N Awasthi… - Cancer Research, 2024 - AACR
Background: Esophageal adenocarcinoma (EAC) is one the deadliest cancers in United
States (US) and the only major cancer in the US with increasing incidence. Gastroesophageal …

[HTML][HTML] Immunization uptake and its determinants among the internal migrant population living in nonnotified slums of Hyderabad city, India

JB Geddam, PR Kommu, SN Ponna… - Journal of family …, 2018 - journals.lww.com
Background: The aim of this study is to assess the childhood immunization uptake and its
determinants among the internal migrant population living in nonnotified slums of Hyderabad …