Empirical fitness landscapes reveal accessible evolutionary paths
When attempting to understand evolution, we traditionally rely on analysing evolutionary
outcomes, despite the fact that unseen intermediates determine its course. A handful of recent …
outcomes, despite the fact that unseen intermediates determine its course. A handful of recent …
Room-temperature transistor based on a single carbon nanotube
The use of individual molecules as functional electronic devices was first proposed in the
1970s ( 1 ). Since then, molecular electronics 2 , 3 has attracted much interest, particularly …
1970s ( 1 ). Since then, molecular electronics 2 , 3 has attracted much interest, particularly …
Individual single-wall carbon nanotubes as quantum wires
Carbon nanotubes have been regarded since their discovery 1 as potential molecular quantum
wires. In the case of multi-wall nanotubes, where many tubes are arranged in a coaxial …
wires. In the case of multi-wall nanotubes, where many tubes are arranged in a coaxial …
The bacteriophage φ29 portal motor can package DNA against a large internal force
As part of the viral infection cycle, viruses must package their newly replicated genomes for
delivery to other host cells. Bacteriophage φ29 packages its 6.6-µm long, double-stranded …
delivery to other host cells. Bacteriophage φ29 packages its 6.6-µm long, double-stranded …
Long‐term expanding human airway organoids for disease modeling
Organoids are self‐organizing 3D structures grown from stem cells that recapitulate essential
aspects of organ structure and function. Here, we describe a method to establish long‐term…
aspects of organ structure and function. Here, we describe a method to establish long‐term…
Stochasticity of metabolism and growth at the single-cell level
… Heinemann and members of the Tans group for reading the manuscript. … Now Sander Tans
and colleagues use time-lapse microscopy to accurately determine the growth rate of single …
and colleagues use time-lapse microscopy to accurately determine the growth rate of single …
SecB—a chaperone dedicated to protein translocation
P Bechtluft, N Nouwen, SJ Tans… - Molecular BioSystems, 2010 - pubs.rsc.org
SecB is a molecular chaperone in Gram-negative bacteria dedicated to the post-translational
translocation of proteins across the cytoplasmic membrane. The entire surface of this …
translocation of proteins across the cytoplasmic membrane. The entire surface of this …
Building plasmonic nanostructures with DNA
Plasmonic structures can be constructed from precise numbers of well-defined metal
nanoparticles that are held together with molecular linkers, templates or spacers. Such structures …
nanoparticles that are held together with molecular linkers, templates or spacers. Such structures …
Temperature-dependent resistivity of single-wall carbon nanotubes
…, RE Smalley, ARM Verschueren, SJ Tans… - Europhysics …, 1998 - iopscience.iop.org
Samples of single-wall carbon nanotubes containing tubes with an" armchair" wrapping have
been produced and exhibit metallic behavior with an intrinsic resistivity which increases …
been produced and exhibit metallic behavior with an intrinsic resistivity which increases …
Multiprobe transport experiments on individual single-wall carbon nanotubes
… It is of interest to compare our results to those obtained on a single tube [17] by Tans et al.
[5]. From twoprobe transport data they concluded that the electron wave function was spatially …
[5]. From twoprobe transport data they concluded that the electron wave function was spatially …