General cognitive function is a prominent and relatively stable human trait that is associated
with many important life outcomes. We combine cognitive and genetic data from the …

Understanding the determinants of socioeconomic status (SES) is an important economic and
social goal. Several major influences on SES are known, yet much of the variance in SES …

Sex differences in the human brain are of interest for many reasons: for example, there are
sex differences in the observed prevalence of psychiatric disorders and in some …

… SJ Ritchie performed the literature search and the initial data coding, then both authors … ,
which were adapted for these analyses by SJ Ritchie. SJ Ritchie wrote the R analysis scripts (for …

Age-associated disease and disability are placing a growing burden on society. However,
ageing does not affect people uniformly. Hence, markers of the underlying biological ageing …

Genetic correlations estimated from genome-wide association studies (GWASs) reveal
pervasive pleiotropy across a wide variety of phenotypes. We introduce genomic structural …

Cognitive ability and educational success predict positive outcomes across the lifespan, from
higher earnings to better health and longevity. The shared positive outcomes associated …

Background: The DNA methylation-based ‘epigenetic clock’ correlates strongly with
chronological age, but it is currently unclear what drives individual differences. We examine cross-…

Quantifying the microstructural properties of the human brain’s connections is necessary for
understanding normal ageing and disease. Here we examine brain white matter magnetic …

People’s differences in cognitive functions are partly heritable and are associated with important
life outcomes. Previous genome-wide association (GWA) studies of cognitive functions …