… the TR2 motif in ERp57–tapasin conjugates can be modified by oxidising reagents, suggesting
that TR2 is available to undergo redox reactions with substrates (A Antoniou and S Powis…

A pool of MHC-I molecules present at the plasma membrane can dissociate from the peptide
and/or the light chain, becoming open MHC-I conformers. Whereas peptide-bound MHC-I …

Non‐classical MHC class I molecule HLA‐E is the ligand for CD94 / NKG2 NK cell receptors.
Surface expression of HLA‐E requires binding of specific HLA class I leader sequences. …

Nanoparticle tracking analysis permits the determination of both the size distribution and
relative concentration of microvesicles, including exosomes, in the supernatants of cultured …

The ‘MHC-I (major histocompatibility complex class I)-opathy’ concept describes a family of
inflammatory conditions with overlapping clinical manifestations and a strong genetic link to …

IN mammalian cells, short peptides derived from intracellular proteins are displayed on the
cell membrane associated with class I molecules of the major histocompatibility complex (…

We report on a laser that is fully embedded within a single live cell. By harnessing natural
endocytosis of the cell, we introduce a fluorescent whispering gallery mode (WGM) …

Autism spectrum condition (ASC) is recognized as having an inflammatory component. Post-mortem
brain samples from patients with ASC display neuroglial activation and …

Short antigenic peptides bound in the groove of class I major histocompatibility complex
molecules enable T cells to detect intracellular pathogens. It has been assumed that structural …

An important mammalian defence strategy against intracellular pathogens is the presentation
of cytoplasmically derived short peptides by major histocompatibility complex (MHC) class …