The virulence of a virus is determined by its ability to adversely affect the host cell, host
organism or population of host organisms. Influenza A viruses have been responsible for four …

… Furthermore, although detection of CVI988 in feather tips is delayed when compared with
the lymphoid tissues, it replicates to significantly greater levels in feather tips (Baigent, …

Could some vaccines drive the evolution of more virulent pathogens? Conventional wisdom
is that natural selection will remove highly lethal pathogens if host death greatly reduces …

The influence on virus replication in culture of the presence and location of glycosylation
sites on the haemagglutinin (HA) glycoprotein of avian influenza viruses and differences in …

Notwithstanding the well-characterised roles of a number of oncogenes in neoplastic
transformation, microRNAs (miRNAs) are increasingly implicated in several human cancers. …

A real-time PCR method was developed, optimised and validated, to enable quantitation of
Marek's disease virus genomes as copy number per million host cells. The duplex PCR …

Publisher Summary This chapter describes the biology and life cycle of Marek's disease
virus (MDV). Marek's disease virus spreads by indirect contact and can remain infectious for …

Marek’s disease virus (MDV) is an oncogenic herpesvirus that induces fatal T cell lymphomas
in chickens. With more than 20 billion doses of vaccine used annually, vaccination …

… It is also noteworthy that induction of MxA is stimulated in cells infected with cp BVDV that
had been subjected to gradient purification (SJ Baigent and A. Pande, unpublished data), …

Marek's disease virus (MDV) is classified as an oncogenic lymphotropic herpesvirus of
chickens. MDV productively and cytolytically infects B, αβT and γδT lymphocytes and latently …