Enhancer remodeling during adaptive bypass to MEK inhibition is attenuated by pharmacologic targeting of the P-TEFb complex
…, JS Duncan, MC Whittle, SP Angus, SH Velarde… - Cancer discovery, 2017 - AACR
Targeting the dysregulated BRAF–MEK–ERK pathway in cancer has increasingly emerged
in clinical trial design. Despite clinical responses in specific cancers using inhibitors …
in clinical trial design. Despite clinical responses in specific cancers using inhibitors …
[HTML][HTML] Proteomic analysis defines kinase taxonomies specific for subtypes of breast cancer
Multiplexed small molecule inhibitors covalently bound to Sepharose beads (MIBs) were
used to capture functional kinases in luminal, HER2-enriched and triple negative (basal-like …
used to capture functional kinases in luminal, HER2-enriched and triple negative (basal-like …
Drops, liquid layers and the Marangoni effect
MG Velarde - … Transactions of the Royal Society of …, 1998 - royalsocietypublishing.org
An overview is given of recent results about the onset and development of steady and time–dependent
flow motions past an instability threshold induced by the Marangoni effect. First, I …
flow motions past an instability threshold induced by the Marangoni effect. First, I …
Abstract A30: Kinome dynamics in triple negative breast cancer in response to chemotherapy
SH Velarde, J Usary, C Perou, GL Johnson - Clinical Cancer Research, 2017 - AACR
Triple negative breast cancers (TNBC) have lower expression levels of the receptors (estrogen,
progesterone, Her2) used in targeted therapy than other breast cancer subtypes. This …
progesterone, Her2) used in targeted therapy than other breast cancer subtypes. This …
Abstract B24: Triple-negative breast cancer adaptive response to MEK inhibition is regulated by the induction of super-enhancers
…, TJ Stuhlmiller, D Singh, N Sciaky, SH Velarde… - Molecular Cancer …, 2016 - AACR
A predominant mechanism by which cancer cells circumvent the action of targeted kinase
inhibitors is the activation of bypass signaling networks that reactivate cellular proliferation. In …
inhibitors is the activation of bypass signaling networks that reactivate cellular proliferation. In …
Evidence for interhemispheric mercury exchange in the Pacific Ocean upper troposphere
…, M Andrade, I Moreno, F Velarde… - Journal of …, 2022 - Wiley Online Library
… mercury difference to large emissions from SH oceans or to the exchange of airborne …
We examine and exclude potential SH sources for this increase, such as mercury emissions …
We examine and exclude potential SH sources for this increase, such as mercury emissions …
Pablita Velarde
S Hyer - Art Journal, 1994 - search.proquest.com
… Velarde struggled to establish herself as an artist in the 1940s and … Velarde was not only the
first Pueblo woman to pursue a … SH: How has age affected the content of your work? PV: The …
first Pueblo woman to pursue a … SH: How has age affected the content of your work? PV: The …
[HTML][HTML] Seasonality of the particle number concentration and size distribution: a global analysis retrieved from the network of Global Atmosphere Watch (GAW) near …
…, V Vakkari, PG Van Zyl, F Velarde… - Atmospheric …, 2021 - acp.copernicus.org
Aerosol particles are a complex component of the atmospheric system that influences climate
directly by interacting with solar radiation, and indirectly by contributing to cloud formation. …
directly by interacting with solar radiation, and indirectly by contributing to cloud formation. …
[HTML][HTML] In situ vaccination via tissue-targeted cDC1 expansion enhances the immunogenicity of chemoradiation and immunotherapy
…, HF Tu, C Huang, B Lee, E Velarde… - The Journal of …, 2024 - Am Soc Clin Investig
Even with the prolific clinical use of next-generation cancer therapeutics, many tumors remain
unresponsive or become refractory to therapy, creating a medical need. In cancer, DCs …
unresponsive or become refractory to therapy, creating a medical need. In cancer, DCs …
Consistency in the sum frequency generation intensity and phase vibrational spectra of the air/neat water interface
R Feng, Y Guo, R Lü, L Velarde… - The Journal of Physical …, 2011 - ACS Publications
… SH signal on the reference crystal, and this SH signal then interferes with the SH signal
generated from the liquid surface. Because this interference occurs only when these two SH …
generated from the liquid surface. Because this interference occurs only when these two SH …