User profiles for S. H. Ong

Sim-Heng Ong

- Verified email at nus.edu.sg - Cited by 9034

SH Ong

- Verified email at ucsiuniversity.edu.my - Cited by 4120

Swee Hoe Ong

- Verified email at sanger.ac.uk - Cited by 3398

Image analysis by Tchebichef moments

R Mukundan, SH Ong, PA Lee - IEEE Transactions on image …, 2001 - ieeexplore.ieee.org
This paper introduces a new set of orthogonal moment functions based on the discrete
Tchebichef polynomials. The Tchebichef moments can be effectively used as pattern features in …

LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets

…, PPK Aw, D Bertrand, GHT Yeo, SH Ong… - Nucleic acids …, 2012 - academic.oup.com
The study of cell-population heterogeneity in a range of biological systems, from viruses to
bacterial isolates to tumor samples, has been transformed by recent advances in sequencing …

Image analysis by Krawtchouk moments

PT Yap, R Paramesran, SH Ong - IEEE Transactions on image …, 2003 - ieeexplore.ieee.org
A new set of orthogonal moments based on the discrete classical Krawtchouk polynomials
is introduced. The Krawtchouk polynomials are scaled to ensure numerical stability, thus …

[HTML][HTML] Eating disorder outcomes: findings from a rapid review of over a decade of research

J Miskovic-Wheatley, E Bryant, SH Ong, S Vatter… - Journal of Eating …, 2023 - Springer
Background Eating disorders (ED), especially Anorexia Nervosa (AN), are internationally
reported to have amongst the highest mortality and suicide rates in mental health. With limited …

Medical image segmentation using k-means clustering and improved watershed algorithm

HP Ng, SH Ong, KWC Foong, PS Goh… - 2006 IEEE southwest …, 2006 - ieeexplore.ieee.org
We propose a methodology that incorporates k-means and improved watershed segmentation
algorithm for medical image segmentation. The use of the conventional watershed …

Integrating spatial fuzzy clustering with level set methods for automated medical image segmentation

BN Li, CK Chui, S Chang, SH Ong - Computers in biology and medicine, 2011 - Elsevier
The performance of the level set segmentation is subject to appropriate initialization and
optimal configuration of controlling parameters, which require substantial manual intervention. …

FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors

SH Ong, GR Guy, YR Hadari, S Laks… - … and cellular biology, 2000 - Taylor & Francis
The docking protein FRS2 was implicated in the transmission of extracellular signals from
the fibroblast growth factor (FGF) or nerve growth factor (NGF) receptors to the Ras/mitogen-…

A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling

…, M Falasca, Z Zhang, SH Ong… - … and cellular biology, 2000 - Taylor & Francis
The Gab1 protein is tyrosine phosphorylated in response to various growth factors and serves
as a docking protein that recruits a number of downstream signaling proteins, including …

[HTML][HTML] Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region

LE Wybenga-Groot, B Baskin, SH Ong, J Tong… - Cell, 2001 - cell.com
The Eph receptor tyrosine kinase family is regulated by autophosphorylation within the
juxtamembrane region and the kinase activation segment. We have solved the X-ray crystal …

Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins

SH Ong, YR Hadari, N Gotoh, GR Guy… - Proceedings of the …, 2001 - National Acad Sciences
The docking protein FRS2 is a major downstream effector that links fibroblast growth factor (FGF)
and nerve growth factor receptors with the Ras/mitogen-activated protein kinase …