… Byars … The change in the mean of z between generations is sg/σ z 2 . … Byars was
incorrect. This has now been corrected in all versions of the article. …

Between the 1930s and 1950s, scientists developed key principles of population genetics to
try and explain the aging process. Almost a century later, these aging theories, including …

Aims Genetics plays an important role in coronary heart disease (CHD) but the clinical utility
of genomic risk scores (GRSs) relative to clinical risk scores, such as the Framingham Risk …

Alpine environments are particularly susceptible to environmental changes associated with
global warming but there is potential for alpine plants to adapt to warming if local adaptation …

Our aims were to demonstrate that natural selection is operating on contemporary humans,
predict future evolutionary change for specific traits with medical significance, and show that …

… Author Contributions: Dr Byars had full access to all of the data in the study and takes
responsibility … SG Byars was also funded by a Marie Curie International Incoming Fellowship …

Background Complex diseases are characterized by multiple subtle perturbations to
biological processes. New omics platforms can detect these perturbations, but translating the …

Background Cardiac hypertrophy increases the risk of developing heart failure and cardiovascular
death. The neutrophil inflammatory protein, lipocalin‐2 ( LCN 2/ NGAL ), is elevated in …

Background and Aims The persistence of plants inhabiting restricted alpine areas under
climate change will depend upon many factors including levels of genetic variation in adaptive …

Opposite phenotypic and behavioural traits associated with copy number variation and
disruptions to imprinted genes with parent-of-origin effects have led to the hypothesis that autism …