The role of estrogen in the regulation of the inflammatory response is not well defined. In this
study, we investigated the effects of ovarian hormones on the acute inflammatory response …

Hairless rats were topically treated with a combination of 10% curcumin and 3% ginger
extract (or with each agent alone) for a 21‐day period. Following this, the rats were treated …

Airway instillation into rats of 2‐chloroethyl ethyl sulfide (CEES), the half molecule of sulfur
mustard compound, results in acute lung injury, as measured by the leak of plasma albumin …

Multiorgan apoptosis occurs during sepsis. Following cecal ligation and puncture (CLP) in
rats, thymocytes underwent apoptosis in a time-dependent manner. C5a blockade …

Stat3 plays diverse roles in biological processes including cell proliferation, survival, apoptosis,
and inflammation. Very little is known regarding its activation and function in the lung …

The intestine is maintained by stem cells located at the base of crypts and distinguished by
the expression of LGR5. Genetically engineered mouse models have provided a wealth of …

Partial hepatectomy triggers hepatocyte proliferation, hepatic matrix remodeling, and
hepatocyte apoptosis, all of which are important processes in the regenerating liver. Previous …

Sepsis is associated with extensive complement activation, compromising innate immune
defenses, especially in neutrophils (PMN). Recently, a second C5a receptor (C5L2) was …

The chemical warfare agent analog, 2‐chloroethyl ethyl sulfide, known as ‘half‐mustard gas’
(HMG), is less toxic and less of an environmental hazard than the full molecule and has …

We recently showed that acute oxidant-related lung injury (ALI) in rats after application of 2-chloroethyl
ethyl sulfide (CEES) is attenuated by the airway instillation of antioxidants. We …