User profiles for S. D. Kyle

Simon D. Kyle

University of Oxford
Verified email at ndcn.ox.ac.uk
Cited by 10305

Insomnia and health-related quality of life

SD Kyle, K Morgan, CA Espie - Sleep medicine reviews, 2010 - Elsevier
Health-related Quality of Life (HRQoL) has become an important construct in contemporary
medicine and health care, permitting assessment of disorder burden and evaluation of …

Insomnia disorder: State of the science and challenges for the future

…, R Wassing, AL Henry, SD Kyle… - Journal of sleep …, 2022 - Wiley Online Library
Insomnia disorder comprises symptoms during night and day that strongly affect quality of
life and wellbeing. Prolonged sleep latency, difficulties to maintain sleep and early morning …

[HTML][HTML] Social interactions, emotion and sleep: A systematic review and research agenda

L Beattie, SD Kyle, CA Espie, SM Biello - Sleep medicine reviews, 2015 - Elsevier
… This could be relevant to the results of Kyle, Espie and Morgan [70], who found that … For
example, Kyle et al. [94] reported differences between normal sleepers and insomnia participants …

A randomized, placebo-controlled trial of online cognitive behavioral therapy for chronic insomnia disorder delivered via an automated media-rich web application

CA Espie, SD Kyle, C Williams, JC Ong, NJ Douglas… - Sleep, 2012 - academic.oup.com
… ) of 136.5 min (SD 72.5) and mean self-reported SE of 61.3% (SD 16.2) for the sample as a
… 5.09 h (SD 1.47). On the SCI, the overall mean score of 2.98 (SD 1.04) was > 4 SD below the …

The Sleep Condition Indicator: a clinical screening tool to evaluate insomnia disorder

CA Espie, SD Kyle, P Hames, M Gardani, L Fleming… - BMJ open, 2014 - bmjopen.bmj.com
… Simon D Kyle3, … The mean SCI values for the ‘probable insomnia disorder’ category were
10.7 (SD=5.3) vs 22.9 (SD=6.2) for ‘no insomnia disorder’ (t=9.86, p<0.0001). Applying an SCI …

[HTML][HTML] Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates

…, J Bowden, BE Cade, M Garaulet, SD Kyle… - Nature …, 2019 - nature.com
Sleep is an essential state of decreased activity and alertness but molecular factors regulating
sleep duration remain unknown. Through genome-wide association analysis in 446,118 …

Effect of digital cognitive behavioral therapy for insomnia on health, psychological well-being, and sleep-related quality of life: a randomized clinical trial

CA Espie, R Emsley, SD Kyle, C Gordon… - JAMA …, 2019 - jamanetwork.com
… Cohen d standardized effect sizes were estimated by dividing the adjusted between-group
difference by the baseline pooled SD of the corresponding outcome. Assumptions of …

Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits

…, AI Luik, A Loudon, FAJL Scheer, SM Purcell, SD Kyle… - Nature …, 2017 - nature.com
Chronic sleep disturbances, associated with cardiometabolic diseases, psychiatric disorders
and all-cause mortality 1 , 2 , affect 25–30% of adults worldwide 3 . Although environmental …

[HTML][HTML] Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UK Biobank

JM Lane, I Vlasac, SG Anderson, SD Kyle… - Nature …, 2016 - nature.com
Our sleep timing preference, or chronotype, is a manifestation of our internal biological clock.
Variation in chronotype has been linked to sleep disorders, cognitive and physical …

Biological and clinical insights from genetics of insomnia symptoms

…, CJ Willer, S Redline, K Spiegelhalder, SD Kyle… - Nature …, 2019 - nature.com
… )), diminished subjective well-being (difference in mean sd units of –0.29 (se 0.06)), and
greater depressive symptoms (difference in mean sd units of 0.42 (se 0.08)); all associations …