User profiles for S. . Pååbo

Svante Paabo

Verified email at eva.mpg.de
Cited by 136158

Genetic analyses from ancient DNA

S Pääbo, H Poinar, D Serre… - Annu. Rev …, 2004 - annualreviews.org
… , which is eliminated when the template DNA is treated with … sets of sequences is observed
(58), a third amplification is in … variants is reproducible, provided that what is studied are …

ancient DNA

…, D Serre, HN Poinar, M Kuch, S Pääbo - Nature Reviews …, 2001 - nature.com
… The reason is that human DNA is particularly prevalent in the environment of laboratories
and museums, and cannot easily be distinguished from the DNA endogenous to ancient …

Generation times in wild chimpanzees and gorillas suggest earlier divergence times in great ape and human evolution

…, K Zuberbühler, S Pääbo… - Proceedings of the …, 2012 - National Acad Sciences
Fossils and molecular data are two independent sources of information that should in principle
provide consistent inferences of when evolutionary lineages diverged. Here we use an …

Dynamics of mitochondrial DNA evolution in animals: amplification and sequencing with conserved primers.

…, A Meyer, SV Edwards, S Pääbo… - Proceedings of the …, 1989 - National Acad Sciences
… When applied to mtDNA, the restriction method is reliable only among closely related taxa.
Restriction analysis is limited to the small proportion of species inthe biosphere that are big …

A draft sequence of the Neandertal genome

…, R Nielsen, J Kelso, M Lachmann, D Reich, S Pääbo - science, 2010 - science.org
Neandertals, the closest evolutionary relatives of present-day humans, lived in large parts of
Europe and western Asia before disappearing 30,000 years ago. We present a draft …

The complete genome sequence of a Neanderthal from the Altai Mountains

…, B Viola, M Slatkin, D Reich, J Kelso, S Pääbo - Nature, 2014 - nature.com
We present a high-quality genome sequence of a Neanderthal woman from Siberia. We
show that her parents were related at the level of half-siblings and that mating among close …

Molecular evolution of FOXP2, a gene involved in speech and language

…, CSL Lai, V Wiebe, T Kitano, AP Monaco, S Pääbo - Nature, 2002 - nature.com
… of variability recovered at FOXP2, it is noteworthy that the next gene is located 286 kilobases
(kb) away from the sequenced segment. A selective sweep is not expected to lead to an …

[HTML][HTML] Genetic history of an archaic hominin group from Denisova Cave in Siberia

…, AP Derevianko, JJ Hublin, J Kelso, M Slatkin, S Pääbo - Nature, 2010 - nature.com
… A fundamental question is whether the Denisova individual is an outgroup to Neanderthals
and modern humans, as the mtDNA suggests 19 , whether it is a sister group to Neanderthals …

A high-coverage genome sequence from an archaic Denisovan individual

…, EE Eichler, M Slatkin, D Reich, J Kelso, S Pääbo - Science, 2012 - science.org
… Note that the D-statistic is not the same as the mixture proportion, as it is also affected, for
example, by the amount of genetic drift that is shared between the samples. (B) Sharing of …

Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome

M Weber, I Hellmann, MB Stadler, L Ramos, S Pääbo… - Nature …, 2007 - nature.com
… , it is established that methylation of CpG-rich promoters is … Equally uncertain is the contribution
of promoter DNA methylation to … This inconclusive picture is a consequence of the limited …