User profiles for R. van Amerongen

Renée van Amerongen

Associate professor, University of Amsterdam
Verified email at uva.nl
Cited by 5855

Towards an integrated view of Wnt signaling in development

R van Amerongen, R Nusse - Development, 2009 - journals.biologists.com
Wnt signaling is crucial for embryonic development in all animal species studied to date.
The interaction between Wnt proteins and cell surface receptors can result in a variety of …

Alternative wnt signaling is initiated by distinct receptors

R van Amerongen, A Mikels, R Nusse - Science signaling, 2008 - science.org
An unanswered question in the field of signal transduction research is how different signaling
pathways are activated with strict specificity in a temporally and spatially controlled manner…

[PDF][PDF] Generating cellular diversity and spatial form: Wnt signaling and the evolution of multicellular animals

KM Loh, R van Amerongen, R Nusse - Developmental cell, 2016 - cell.com
There were multiple prerequisites to the evolution of multicellular animal life, including the
generation of multiple cell fates ("cellular diversity") and their patterned spatial arrangement ("…

[PDF][PDF] Developmental stage and time dictate the fate of Wnt/β-catenin-responsive stem cells in the mammary gland

R Van Amerongen, AN Bowman, R Nusse - Cell stem cell, 2012 - cell.com
The mammary epithelium undergoes extensive growth and remodeling during pregnancy,
suggesting a role for stem cells. Yet their origin, identity, and behavior in the intact tissue …

Interfollicular epidermal stem cells self-renew via autocrine Wnt signaling

…, CJ Kuo, R Van Amerongen, AM Klein, R Nusse - Science, 2013 - science.org
The skin is a classical example of a tissue maintained by stem cells. However, the identity of
the stem cells that maintain the interfollicular epidermis and the source of the signals that …

A general-purpose version of the fast decoupled load flow

RAM Van Amerongen - IEEE Transactions on Power Systems, 1989 - ieeexplore.ieee.org
… ROBERT VAN AMERONGEN: we very much appreciate the contributions made by the
discussion participants. It is good to see that they largely confirm the main result of …

[HTML][HTML] Wnt5a can both activate and repress Wnt/β-catenin signaling during mouse embryonic development

R van Amerongen, C Fuerer, M Mizutani, R Nusse - Developmental biology, 2012 - Elsevier
Embryonic development is controlled by a small set of signal transduction pathways, with vastly
different phenotypic outcomes depending on the time and place of their recruitment. How …

Wnt signalling: conquering complexity

KE Wiese, R Nusse, R van Amerongen - Development, 2018 - journals.biologists.com
… by van Amerongen, 2012). We will come back to these responses in more detail below, but
not before we take a closer look at how the first individual players were originally discovered. …

Alternative Wnt pathways and receptors

R Van Amerongen - Cold Spring Harbor perspectives in …, 2012 - cshperspectives.cshlp.org
R van Amerongen and R Nusse, unpubl.). Of note, Wnt5a/Ror2 signaling has also been
reported to inhibit convergent extension movements through the activation of JNK/AP-1 (Oishi et …

[PDF][PDF] In vivo clonal analysis reveals lineage-restricted progenitor characteristics in mammalian kidney development, maintenance, and regeneration

…, AM Newman, JM Tsai, X Lim, R Van-Amerongen… - Cell reports, 2014 - cell.com
The mechanism and magnitude by which the mammalian kidney generates and maintains
its proximal tubules, distal tubules, and collecting ducts remain controversial. Here, we use …