User profiles for R. Veldhuizen
Ruud VeldhuizenWestern University Verified email at uwo.ca Cited by 9219 |
[HTML][HTML] The role of lipids in pulmonary surfactant
R Veldhuizen, K Nag, S Orgeig, F Possmayer - Biochimica et Biophysica …, 1998 - Elsevier
Pulmonary surfactant is composed of approx. 90% lipids and 10% protein. This review
article focusses on the lipid components of surfactant. The first sections will describe the lipid …
article focusses on the lipid components of surfactant. The first sections will describe the lipid …
[HTML][HTML] Current perspectives in pulmonary surfactant—inhibition, enhancement and evaluation
Pulmonary surfactant (PS) is a complicated mixture of approximately 90% lipids and 10%
proteins. It plays an important role in maintaining normal respiratory mechanics by reducing …
proteins. It plays an important role in maintaining normal respiratory mechanics by reducing …
The role of exogenous surfactant in the treatment of acute lung injury
JF Lewis, R Veldhuizen - Annual review of physiology, 2003 - annualreviews.org
▪ Abstract A number of conditions, such as pneumonia, trauma, or systemic sepsis arising
from the gut, may result in the acute respiratory distress syndrome (ARDS). Because of its …
from the gut, may result in the acute respiratory distress syndrome (ARDS). Because of its …
[HTML][HTML] Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury
Multiple lung pathogens such as chemical agents, H5N1 avian flu, or SARS cause high
lethality due to acute respiratory distress syndrome. Here we report that Toll-like receptor 4 (TLR4…
lethality due to acute respiratory distress syndrome. Here we report that Toll-like receptor 4 (TLR4…
Pseudomonas aeruginosa protease IV degrades surfactant proteins and inhibits surfactant host defense and biophysical functions
JL Malloy, RAW Veldhuizen… - … of Physiology-Lung …, 2005 - journals.physiology.org
Pulmonary surfactant has two distinct functions within the lung: reduction of surface tension
at the air-liquid interface and participation in innate host defense. Both functions are …
at the air-liquid interface and participation in innate host defense. Both functions are …
Pulmonary surfactant subfractions in patients with the acute respiratory distress syndrome.
RA Veldhuizen, LA McCaig, T Akino… - American journal of …, 1995 - atsjournals.org
Changes in the surfactant system have been observed in patients with acute respiratory
distress syndrome (ARDS). These alterations in surfactant are thought to contribute to lung …
distress syndrome (ARDS). These alterations in surfactant are thought to contribute to lung …
Pulmonary surfactant: A mighty thin film
F Possmayer, YY Zuo, RAW Veldhuizen… - Chemical …, 2023 - ACS Publications
Pulmonary surfactant is a critical component of lung function in healthy individuals. It
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing with …
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing with …
Analysis of the performance of pathologists in the grading of bladder tumors
…, WAD Anderson, CL Alons, ME Boon, RW Veldhuizen - Human Pathology, 1983 - Elsevier
Fifty-seven transurethrally resected bladder tumors were analyzed to determine whether
different pathologists, using the World Health Organization grading system, graded the same …
different pathologists, using the World Health Organization grading system, graded the same …
[HTML][HTML] A modified squeeze-out mechanism for generating high surface pressures with pulmonary surfactant
…, NO Petersen, F Possmayer, RAW Veldhuizen - … et Biophysica Acta (BBA …, 2012 - Elsevier
The exact mechanism by which pulmonary surfactant films reach the very low surface
tensions required to stabilize the alveoli at end expiration remains uncertain. We utilized the …
tensions required to stabilize the alveoli at end expiration remains uncertain. We utilized the …
Lung lavage and surfactant replacement during ex vivo lung perfusion for treatment of gastric acid aspiration–induced donor lung injury
…, JF Lewis, M Post, RAW Veldhuizen… - The Journal of Heart and …, 2017 - Elsevier
Background Ex vivo lung perfusion (EVLP) provides opportunities to treat injured donor
lungs before transplantation. We investigated whether lung lavage, to eliminate inflammatory …
lungs before transplantation. We investigated whether lung lavage, to eliminate inflammatory …