Mass spectral databases for LC/MS-and GC/MS-based metabolomics: State of the field and future prospects

…, S Neumann, M Navarro, RM Salek… - TrAC Trends in …, 2016 - Elsevier
At present, mass spectrometry (MS)-based metabolomics has been widely used to obtain
new insights into human, plant, and microbial biochemistry; drug and biomarker discovery; …

NMR-based metabolomics in human disease diagnosis: applications, limitations, and recommendations

AHM Emwas, RM Salek, JL Griffin, J Merzaban - Metabolomics, 2013 - Springer
Metabolomics is a dynamic and emerging research field, similar to proteomics, transcriptomics
and genomics in affording global understanding of biological systems. It is particularly …

[HTML][HTML] Standardizing the experimental conditions for using urine in NMR-based metabolomic studies with a particular focus on diagnostic studies: a review

…, C Luchinat, P Turano, L Tenori, R Roy, RM Salek… - Metabolomics, 2015 - Springer
The metabolic composition of human biofluids can provide important diagnostic and prognostic
information. Among the biofluids most commonly analyzed in metabolomic studies, urine …

MetaboLights—an open-access general-purpose repository for metabolomics studies and associated meta-data

K Haug, RM Salek, P Conesa, J Hastings… - Nucleic acids …, 2013 - academic.oup.com
… An R package has been developed to facilitate data analysis (Supplementary Method). The
Risa module, available in the next BioConductor release, includes functionality to process …

A metabolomic comparison of urinary changes in type 2 diabetes in mouse, rat, and human

RM Salek, ML Maguire, E Bentley… - Physiological …, 2007 - journals.physiology.org
… *RM Salek and ML Maguire contributed equally to this work. … *RM Salek and ML Maguire
contributed equally to this work. … * RM Salek and ML Maguire contributed equally to this work. …

The role of reporting standards for metabolite annotation and identification in metabolomic studies

RM Salek, C Steinbeck, MR Viant, R Goodacre… - …, 2013 - academic.oup.com
The application of reporting standards in metabolomics allow data from different laboratories
to be shared, integrated and interpreted. Although minimum reporting standards related to …

[HTML][HTML] Navigating freely-available software tools for metabolomics analysis

R Spicer, RM Salek, P Moreno, D Cañueto… - Metabolomics, 2017 - Springer
Introduction The field of metabolomics has expanded greatly over the past two decades, both
as an experimental science with applications in many areas, as well as in regards to data …

MetaboLights: an open‐access database repository for metabolomics data

…, RA Spicer, M Williams, X Li, RM Salek… - Current protocols in …, 2016 - Wiley Online Library
MetaboLights is the first general purpose, open‐access database repository for cross‐platform
and cross‐species metabolomics research at the European Bioinformatics Institute (EMBL…

Discovering and linking public omics data sets using the Omics Discovery Index

…, RC Beavis, RM Salek, U Sarkans, R Petryszak… - Nature …, 2017 - nature.com
… YP-R. and MB designed and developed the web and annotation/enrichment framework. …
Nd-T., YP-R. and TT developed the PRIDE reader and contributed to the web development. …

Recommendations and standardization of biomarker quantification using NMR-based metabolomics with particular focus on urinary analysis

…, D Raftery, C Steinbeck, RM Salek… - Journal of proteome …, 2016 - ACS Publications
NMR-based metabolomics has shown considerable promise in disease diagnosis and
biomarker discovery because it allows one to nondestructively identify and quantify large …