User profiles for R. Rockne
 | Russell C. RockneAssociate Professor, Director of Mathematical Oncology and Computational Systems … Verified email at coh.org Cited by 4569 |
[HTML][HTML] The 2019 mathematical oncology roadmap
Whether the nom de guerre is Mathematical Oncology, Computational or Systems Biology,
Theoretical Biology, Evolutionary Oncology, Bioinformatics, or simply Basic Science, there is …
Theoretical Biology, Evolutionary Oncology, Bioinformatics, or simply Basic Science, there is …
Circulating tumor DNA as an early cancer detection tool
Circulating tumor DNA holds substantial promise as an early detection biomarker, particularly
for cancers that do not have currently accepted screening methodologies, such as ovarian, …
for cancers that do not have currently accepted screening methodologies, such as ovarian, …
[HTML][HTML] Patient-specific mathematical neuro-oncology: using a simple proliferation and invasion tumor model to inform clinical practice
…, J Juliano, A Hawkins-Daarud, RC Rockne… - Bulletin of mathematical …, 2015 - Springer
Glioblastoma multiforme (GBM) is the most common malignant primary brain tumor associated
with a poor median survival of 15–18 months, yet there is wide heterogeneity across and …
with a poor median survival of 15–18 months, yet there is wide heterogeneity across and …
Predicting the efficacy of radiotherapy in individual glioblastoma patients in vivo: a mathematical modeling approach
R Rockne, JK Rockhill, M Mrugala… - Physics in Medicine …, 2010 - iopscience.iop.org
… include the effects of XRT, represented by the coefficient R in the loss term. The effect of XRT
… R represents the effect of XRT on the tumor cell population at a location x and time t where …
… R represents the effect of XRT on the tumor cell population at a location x and time t where …
Prognostic significance of growth kinetics in newly diagnosed glioblastomas revealed by combining serial imaging with a novel biomathematical model
…, JM Wardlaw, T Cloughesy, AM Spence, R Rockne… - Cancer research, 2009 - AACR
Glioblastomas are the most aggressive primary brain tumors, characterized by their rapid
proliferation and diffuse infiltration of the brain tissue. Survival patterns in patients with …
proliferation and diffuse infiltration of the brain tissue. Survival patterns in patients with …
Quantifying the Role of Angiogenesis in Malignant Progression of Gliomas: In Silico Modeling Integrates Imaging and Histology
Gliomas are uniformly fatal forms of primary brain neoplasms that vary from low- to high-grade
(glioblastoma). Whereas low-grade gliomas are weakly angiogenic, glioblastomas are …
(glioblastoma). Whereas low-grade gliomas are weakly angiogenic, glioblastomas are …
A mathematical model for brain tumor response to radiation therapy
R Rockne, EC Alvord, JK Rockhill… - Journal of mathematical …, 2009 - Springer
Gliomas are highly invasive primary brain tumors, accounting for nearly 50% of all brain tumors
(Alvord and Shaw in The pathology of the aging human nervous system. Lea & Febiger, …
(Alvord and Shaw in The pathology of the aging human nervous system. Lea & Febiger, …
Quantitative metrics of net proliferation and invasion link biological aggressiveness assessed by MRI with hypoxia assessed by FMISO-PET in newly diagnosed …
Glioblastoma multiforme (GBM) are aggressive and uniformly fatal primary brain tumors
characterized by their diffuse invasion of the normal-appearing parenchyma peripheral to the …
characterized by their diffuse invasion of the normal-appearing parenchyma peripheral to the …
[HTML][HTML] Acquired miR-142 deficit in leukemic stem cells suffices to drive chronic myeloid leukemia into blast crisis
The mechanisms underlying the transformation of chronic myeloid leukemia (CML) from
chronic phase (CP) to blast crisis (BC) are not fully elucidated. Here, we show lower levels of …
chronic phase (CP) to blast crisis (BC) are not fully elucidated. Here, we show lower levels of …
[HTML][HTML] Locoregional delivery of IL-13Rα2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial
…, P Myers-McNamara, M Chen, LD Wang, RC Rockne… - Nature medicine, 2024 - nature.com
Chimeric antigen receptor T cell (CAR-T) therapy is an emerging strategy to improve
treatment outcomes for recurrent high-grade glioma, a cancer that responds poorly to current …
treatment outcomes for recurrent high-grade glioma, a cancer that responds poorly to current …