Inactivation is the process by which an open channel enters a stable nonconducting
conformation after a depolarizing change in membrane potential. Inactivation is a widespread …

This paper is the second of a series of three reviews published in this issue resulting from
the University of California Davis Cardiovascular Symposium 2014: Systems approach to …

We have developed a mathematical model of the mouse ventricular myocyte action potential
(AP) from voltage-clamp data of the underlying currents and Ca 2+ transients. Wherever …

L-type voltage gated calcium channels have an important role in neuronal development by
promoting dendritic growth and arborization. A point mutation in the gene encoding Ca V 1.2 …

The human ether à-go-go-related gene (HERG) encodes a K+ channel that is believed to
be the basis of the delayed rectified current, IKr, in cardiac muscle. We studied HERG …

Toxoplasma gondii is a protozoan pathogen in the phylum Apicomplexa that resides within
an intracellular parasitophorous vacuole (PV) that is selectively permeable to small …

Autism and autism spectrum disorder (ASD) typically arise from a mixture of environmental
influences and multiple genetic alterations. In some rare cases, such as Timothy syndrome (…

The National Heart, Lung, and Blood Institute (NHLBI) convened a workshop of cardiologists,
cardiac electrophysiologists, cell biophysicists, and computational modelers on August 20 …

Aims Familial hypertrophic cardiomyopathy (HCM) is one the most common heart disorders,
with gene mutations in the cardiac sarcomere. Studying HCM with patient-specific induced …

… Mbithi and Rasmus Rasmusson 1977 ISBN 91-7106-121-5 … The other author, Rasmus
Rasmusson, found any reasonable analysis of Kenyan economic and social development …