User profiles for R. Mott

Richard Mott

Weldon Professor of Computational Genetics, University College London, UK
Verified email at ucl.ac.uk
Cited by 41066

Strategies for mapping and cloning quantitative trait genes in rodents

J Flint, W Valdar, S Shifman, R Mott - Nature Reviews Genetics, 2005 - nature.com
Over the past 15 years, more than 2,000 quantitative trait loci (QTLs) have been identified in
crosses between inbred strains of mice and rats, but less than 1% have been characterized …

Finding the molecular basis of quatitative traits: successes and pitfalls

J Flint, R Mott - Nature Reviews Genetics, 2001 - nature.com
Understanding the molecular basis of quantitative genetic variation is a principal goal for
biomedicine. Although the complex genetic architecture of quantitative traits has so far largely …

[HTML][HTML] Multi-parent populations in crops: a toolbox integrating genomics and genetic mapping with breeding

…, RK Varshney, L Venturini, A Whan, J Cockram, R Mott - Heredity, 2020 - nature.com
Crop populations derived from experimental crosses enable the genetic dissection of complex
traits and support modern plant breeding. Among these, multi-parent populations now …

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

…, H Hummerich, S Kirby, M North, S Youngman, R Mott… - Cell, 1993 - cell.com
The Huntington's disease (HD) gene has been mapped in 4p16.3 but has eluded identification.
We have used haplotype analysis of linkage disequilibrium to spotlight a small segment …

[HTML][HTML] Mouse genomic variation and its effect on phenotypes and gene regulation

…, CA Steward, S Bala, J Stalker, R Mott, R Durbin… - Nature, 2011 - nature.com
We report genome sequences of 17 inbred strains of laboratory mice and identify almost ten
times more variants than previously known. We use these genomes to explore the …

[PDF][PDF] 1,135 genomes reveal the global pattern of polymorphism in Arabidopsis thaliana

…, P Korte, C Lanz, CR Lee, D Meng, TP Michael, R Mott… - Cell, 2016 - cell.com
Arabidopsis thaliana serves as a model organism for the study of fundamental physiological,
cellular, and molecular processes. It has also greatly advanced our understanding of …

[HTML][HTML] Multiple reference genomes and transcriptomes for Arabidopsis thaliana

…, C Toomajian, PX Kover, RM Clark, G Rätsch, R Mott - Nature, 2011 - nature.com
Genetic differences between Arabidopsis thaliana accessions underlie the plant’s extensive
phenotypic variation, and until now these have been interpreted largely in the context of the …

[BOOK][B] Machine elements in mechanical design

RL Mott - 2004 - books.google.com
This book provides a practical approach to designing machine elements in the context of
complete mechanical design. This edition retains many features of the previous edition …

[HTML][HTML] Epigenomic diversity in a global collection of Arabidopsis thaliana accessions

…, P Korte, C Lanz, CR Lee, D Meng, TP Michael, R Mott… - Cell, 2016 - cell.com
The epigenome orchestrates genome accessibility, functionality, and three-dimensional
structure. Because epigenetic variation can impact transcription and thus phenotypes, it may …

Recent improvements to the SMART domain-based sequence annotation resource

…, NJ Dickens, T Doerks, J Schultz, R Mott… - Nucleic acids …, 2002 - academic.oup.com
SMART (Simple Modular Architecture Research Tool, http://smart.embl-heidelberg.de ) is a
web-based resource used for the annotation of protein domains and the analysis of domain …