User profiles for R. Kittles

Rick A. Kittles

Professor, Morehouse School of Medicine
Verified email at msm.edu
Cited by 25672

Genetic ancestry and the search for personalized genetic histories

MD Shriver, RA Kittles - Nature Reviews Genetics, 2004 - nature.com
Public demand and the development of large public and private databases of genetic
information across human populations has encouraged the development of the new and rapidly …

Implications of correlations between skin color and genetic ancestry for biomedical research

EJ Parra, RA Kittles, MD Shriver - Nature genetics, 2004 - nature.com
Kittles and collaborators 30 recently described that a marker located in CYP3A4 showed a
significant effect on prostate cancer, but the effect disappeared after controlling for admixture. …

Race, ancestry, and genes: implications for defining disease risk

RA Kittles, KM Weiss - Annual review of genomics and human …, 2003 - annualreviews.org
… We thank Anne Buchanan, Malia Fullerton, Mark Shriver, and Cynthia Winston-Kittles for
their exceedingly helpful discussion of this subject and manuscript. They may not agree with the …

Ancient human genomes suggest three ancestral populations for present-day Europeans

…, R Khusainova, E Khusnutdinova, R Kittles… - Nature, 2014 - nature.com
We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old
hunter-gatherers from Luxembourg and Sweden. We analysed these and other …

SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans

…, I Makalowska, PM McKeigue, D O'donnell, R Kittles… - Science, 2005 - science.org
Lighter variations of pigmentation in humans are associated with diminished number, size,
and density of melanosomes, the pigmented organelles of melanocytes. Here we show that …

[PDF][PDF] Adverse Prognostic Significance of KIT Mutations in Adult Acute Myeloid Leukemia With inv(16) and t(8;21): A Cancer and Leukemia Group B Study

…, K Mrózek, H Chen, RA Kittles… - Journal of Clinical …, 2006 - researchgate.net
… A B S T R A C T … Roskoski R Jr: Structure and regulation of Kit protein-tyrosine kinase:
The stem cell factor receptor. Biochem Biophys Res Commun 338:1307-1315, 2005 18 …

Ancestry informative marker sets for determining continental origin and admixture proportions in common populations in America

…, C Tian, PA White, LM Butler, G Silva, R Kittles… - Human …, 2009 - Wiley Online Library
To provide a resource for assessing continental ancestry in a wide variety of genetic studies,
we identified, validated, and characterized a set of 128 ancestry informative markers (AIMs). …

Skin pigmentation, biogeographical ancestry and admixture mapping

…, L Jin, CJ Hoggart, PM McKeigue, RA Kittles - Human genetics, 2003 - Springer
… (R 2 =0.21, P<0.0001 for the African-American sample and R 2 =0.16, P<0.0001 for the
British African-Caribbean sample). These correlations confirm the validity of the ancestry …

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

…, KL Penney, L Mucci, EM John, SA Ingles, RA Kittles… - Nature …, 2014 - nature.com
Genome-wide association studies (GWAS) have identified 76 variants associated with
prostate cancer risk predominantly in populations of European ancestry. To identify additional …

Latino populations: a unique opportunity for the study of race, genetics, and social environment in epidemiological research

…, JF Arena, R Kittles… - … journal of public …, 2005 - ajph.aphapublications.org
Latinos are the largest minority population in the United States. Although usually classified
as a single ethnic group by researchers, Latinos are heterogeneous from cultural, …