BACKGROUND How do the different cell types in our bodies maintain their distinctive and
characteristic sizes? Although much is known about the signaling networks that stimulate or …

Metabolic reprogramming has been proposed to be a hallmark of cancer, yet a systematic
characterization of the metabolic pathways active in transformed cells is currently lacking. …

A long-standing question in biology is whether there is an intrinsic mechanism for coordinating
growth and the cell cycle in metazoan cells. We examined cell size distributions in …

DNA double-strand breaks are repaired by two main pathways: nonhomologous end joining
(NHEJ) and homologous recombination (HR). The choice between these pathways …

… We especially thank R. Ward for her critique of the paper and the National Institute of General
… Ran Kafri and Jason Levy: These authors contributed equally to this work. … Ran Kafri …

Many crucial components of signal transduction, developmental, and metabolic pathways
have functionally redundant copies. Further, these redundancies show surprising evolutionary …

… The red line represents a quadratic regression fit (a), scoring an adjusted R 2 value of 0.83,
and a logistic regression fit (b) with a P value of 10 −25 . To exclude the possibility that the …

… (University of Minnesota, Minneapolis, MN) for the histological images presented in Figure
1A, as well as Teemu Miettinen, Catherine Royer, Andreas Milias-Argeitis, and Kafri lab …

… Bar-Even for helpful discussions; R. Levy for discussions and critical reviews of the … Bar-Even
for helpful discussions; R. Levy for discussions and critical reviews of the manuscript; and E…

Biomolecular recognition of antigens and epitopes by antibodies is a fundamental event in
the initiation of immune response and plays a central role in a variety of biochemical …