Nuclear pore complexes (NPCs) are huge protein assemblies within the nuclear envelope (NE)
that serve as selective gates for macromolecular transport between nucleus and …

The nuclear pore complex is the main transportation hub for exchange between the cytoplasm
and the nucleus. It is built from nucleoporins that form distinct subcomplexes to establish …

… Juhlin, and B. Huitfeldt). This first reduction resulted in 25 candidate variables: 1) spinal
pain, 2) … Rasch, and R. Scaillet for their participation as monitors of the study, to C. Bini, I. …

Objective. To assess the efficacy and tolerability of sulfasalazine (SSZ) in the treatment of
spondyl‐arthropathy. Methods. We conducted a 6‐month randomized, placebo‐controlled, …

The subcellular compartmentalisation of eukaryotic cells requires selective exchange between
the cytoplasm and the nucleus. Intact nucleocytoplasmic transport is vital for normal cell …

Background Myelodysplasia, infection, restriction of growth, adrenal hypoplasia, genital
phenotypes and enteropathy (MIRAGE) syndrome is a recently described congenital disorder …

Background Triple A syndrome (MIM #231550) is associated with mutations in the AAAS
gene. However, about 30% of patients with triple A syndrome symptoms but an unresolved …

Triple A syndrome is caused by mutations in AAAS encoding the protein ALADIN. We
investigated the role of ALADIN in the human adrenocortical cell line NCI-H295R1 by either over-…

Nucleoporins build the nuclear pore complex (NPC), which, as sole gate for nuclear-cytoplasmic
exchange, is of outmost importance for normal cell function. Defects in the process of …

… Regression models for cell migration rate and wound closure were fitted in R using
package mgcv (version 1.9-0) based on generalized additive models (GAM) 60 . Differences in …