To become resistant, cancer cells need to activate and maintain molecular defense
mechanisms that depend on an energy trade-off between resistance and essential functions. …

Extracellular vesicles (EVs), including exosomes and microvesicles, have been shown to carry
a variety of biomacromolecules including mRNA, microRNA and other non-coding RNAs. …

… Our results show that treatment of mice bearing EMT6 sarcoma with the B1R antagonists
R-954 and R-715 resulted in enhanced doxorubicin penetration after 2 h of treatment (Fig. 3). …

Exposure of phosphatidylserine (PS) on cellular membranes and membrane-derived
microvesicles stimulates a number of anti-inflammatory responses involved in malignant processes…

In previous studies, we determined that β1 integrins from human colon tumors have elevated
levels of α2-6 sialylation, a modification added by β-galactosamide α-2,6-sialyltranferase I (…

In attempts to investigate the role of galectin-3 in innate immunity, we studied galectin-3-deficient
(gal3 −/− ) mice with regard to their response to Toxoplasma gondii infection, which is …

Galectin-3 is a member of the β-galactoside-binding lectin family, whose expression is often
dysregulated in cancers. While galectin-3 is usually an intracellular protein found in the …

Nucleic acid–based assemblies that interact with each other and further communicate with
the cellular machinery in a controlled manner represent a new class of reconfigurable …

… The load-bearing duration R is the elapsed time for which the wall continues to maintain its
… , ie the load-bearing criterion R is always satisfied for the wall studied in the present paper. …

The tumor microenvironment (TME) is a complex environment where cancer cells reside
and interact with different types of cells, secreted factors, and the extracellular matrix. …