User profiles for R. T. Dame
 | Remus T. Dame, PhDLeiden University, Leiden Institute of Chemistry, Centre for Microbial Cell Biology Verified email at chem.leidenuniv.nl Cited by 6587 |
The role of nucleoid‐associated proteins in the organization and compaction of bacterial chromatin
RT Dame - Molecular microbiology, 2005 - Wiley Online Library
The bacterial chromosomal DNA is folded into a compact structure called nucleoid. The
shape and size of this ‘body’ is determined by a number of factors. Major players are DNA …
shape and size of this ‘body’ is determined by a number of factors. Major players are DNA …
The architectural role of nucleoid-associated proteins in the organization of bacterial chromatin: a molecular perspective
The bacterial genome is folded into a compact structure called the nucleoid. Considerable
compaction of the DNA molecule is required in order to reduce its volume below that of the cell…
compaction of the DNA molecule is required in order to reduce its volume below that of the cell…
The major architects of chromatin: architectural proteins in bacteria, archaea and eukaryotes
The genomic DNA of all organisms across the three kingdoms of life needs to be compacted
and functionally organized. Key players in these processes are DNA supercoiling, …
and functionally organized. Key players in these processes are DNA supercoiling, …
[PDF][PDF] CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3
The prokaryotic CRISPR/Cas immune system is based on genomic loci that contain incorporated
sequence tags from viruses and plasmids. Using small guide RNA molecules, these …
sequence tags from viruses and plasmids. Using small guide RNA molecules, these …
Bacterial chromatin organization by H-NS protein unravelled using dual DNA manipulation
Both prokaryotic and eukaryotic organisms contain DNA bridging proteins, which can have
regulatory or architectural functions 1 . The molecular and mechanical details of such …
regulatory or architectural functions 1 . The molecular and mechanical details of such …
Moltemplate: A tool for coarse-grained modeling of complex biological matter and soft condensed matter physics
Coarse-grained models have long been considered indispensable tools in the investigation
of biomolecular dynamics and assembly. However, the process of simulating such models is …
of biomolecular dynamics and assembly. However, the process of simulating such models is …
H-NS mediated compaction of DNA visualised by atomic force microscopy
RT Dame, C Wyman, N Goosen - Nucleic acids research, 2000 - academic.oup.com
The Escherichia coli H-NS protein is a nucleoid-associated protein involved in gene regulation
and DNA compaction. To get more insight into the mechanism of DNA compaction we …
and DNA compaction. To get more insight into the mechanism of DNA compaction we …
Dual architectural roles of HU: formation of flexible hinges and rigid filaments
… Dame and Goosen (7) argue in a recent review that glutaraldehyde cross-linking, necessary
for sample preparation, induced the nucleosome-like structures observed in early electron …
for sample preparation, induced the nucleosome-like structures observed in early electron …
[HTML][HTML] Structural basis for H-NS-mediated trapping of RNA polymerase in the open initiation complex at the rrnB P1
RT Dame, C Wyman, R Wurm, R Wagner… - Journal of Biological …, 2002 - ASBMB
The Escherichia coli H-NS protein is a nucleoid-associated protein involved in both
transcription regulation and DNA compaction. Each of these processes involves H-NS-mediated …
transcription regulation and DNA compaction. Each of these processes involves H-NS-mediated …
Chromosome organization in bacteria: mechanistic insights into genome structure and function
Bacterial chromosomes are folded to compact DNA and facilitate cellular processes. Studying
model bacteria has revealed aspects of chromosome folding that are applicable to many …
model bacteria has revealed aspects of chromosome folding that are applicable to many …