User profiles for R. M. Murphy

Regina Murphy

- Verified email at wisc.edu - Cited by 6252

Robyn M. Murphy

- Verified email at latrobe.edu.au - Cited by 5730

Physical properties data compilations relevant to energy storage, 2. Molten salts: Data on single and multi-component salt systems

…, CB Allen, NP Bansal, RM Murphy… - Nasa Sti/recon …, 1979 - ui.adsabs.harvard.edu
The work provides selected data with value judgments for a set of 49 salt systems of interest
as candidate materials for thermal energy storage sub-systems and for electrochemical …

Mechanisms of exercise intolerance in heart failure with preserved ejection fraction: the role of abnormal peripheral oxygen extraction

BP Dhakal, R Malhotra, RM Murphy… - Circulation: Heart …, 2015 - Am Heart Assoc
Background— Exercise capacity as measured by peak oxygen uptake (Vo 2 ) is similarly
impaired in patients with heart failure with preserved ejection fraction (HFpEF) and heart failure …

[PDF][PDF] Solvent effects on self-assembly of beta-amyloid peptide

CL Shen, RM Murphy - Biophysical journal, 1995 - cell.com
beta-amyloid peptide (A beta) is the primary protein component of senile plaques in Alzheimer's
disease patients. Synthetic A beta spontaneously assembles into amyloid fibrils and is …

[PDF][PDF] A mathematical model of the kinetics of β-amyloid fibril growth from the denatured state

MM Pallitto, RM Murphy - Biophysical journal, 2001 - cell.com
… Heinzelman, LL Kiessling, and RM Murphy. 1999. Recognition … L., MC Fitzgerald, and RM
Murphy. 1994. Effect of acid … L., and RM Murphy. 1995. Solvent effects on self-assembly of …

Correlation of β-amyloid aggregate size and hydrophobicity with decreased bilayer fluidity of model membranes

JJ Kremer, MM Pallitto, DJ Sklansky, RM Murphy - Biochemistry, 2000 - ACS Publications
β-amyloid peptide (Aβ) is the primary constituent of senile plaques, a defining feature of
Alzheimer's disease. Aggregated Aβ is toxic to neurons, but the mechanism of toxicity remains …

Structure− function relationships for inhibitors of β-amyloid toxicity containing the recognition sequence KLVFF

TL Lowe, A Strzelec, LL Kiessling, RM Murphy - Biochemistry, 2001 - ACS Publications
β-Amyloid (Aβ), the primary protein component of Alzheimer's plaques, is neurotoxic when
aggregated into fibrils. We have devised a modular strategy for generating compounds that …

[HTML][HTML] A strategy for designing inhibitors of β-amyloid toxicity

J Ghanta, CL Shen, LL Kiessling, RM Murphy - Journal of Biological …, 1996 - ASBMB
β-Amyloid peptide is the major protein component of Alzheimer's plaques. When aggregated
into amyloid fibrils, the peptide is toxic to neuronal cells. Here, an approach to the design of …

Peptide aggregation in neurodegenerative disease

RM Murphy - Annual review of biomedical engineering, 2002 - annualreviews.org
… A detailed multi-step model of Aβ aggregation kinetics was also proposed by Pallitto &
Murphy (49); a schematic is shown in Figure 2. This pathway included: (a) rapid commitment to …

Recognition sequence design for peptidyl modulators of β-amyloid aggregation and toxicity

…, J Ghanta, P Heinzelman, LL Kiessling, RM Murphy - Biochemistry, 1999 - ACS Publications
β-Amyloid (Aβ), the primary protein component of Alzheimer's plaques, is neurotoxic when
aggregated into fibrils. We have devised a modular strategy for generating compounds that …

Creatine and the creatine transporter: a review

RJ Snow, RM Murphy - Molecular and cellular biochemistry, 2001 - Springer
The cellular role of creatine (Cr) and Cr phosphate (CrP) has been studied extensively in
neural, cardiac and skeletal muscle. Several studies have demonstrated that alterations in the …