Pregnancy rate and first-service conception rate in Angus heifers

…, LR Totir, SD Kachman, RL Fernando… - Journal of animal …, 2006 - academic.oup.com
The objective of this project was to determine the genetic control of conception rate, or
pregnancy percentage in Angus beef heifers. Producers from 6 herds in 5 states provided 3,144 …

A nonsense mutation in cGMP-dependent type II protein kinase (PRKG2) causes dwarfism in American Angus cattle

…, RS Kataria, LR Totir, RL Fernando… - Proceedings of the …, 2009 - National Acad Sciences
Historically, dwarfism was the major genetic defect in US beef cattle. Aggressive culling and
sire testing were used to minimize its prevalence; however, neither of these practices can …

[HTML][HTML] An efficient algorithm to compute marginal posterior genotype probabilities for every member of a pedigree with loops

LR Totir, RL Fernando, J Abraham - Genetics Selection Evolution, 2009 - Springer
Background Marginal posterior genotype probabilities need to be computed for genetic
analyses such as geneticcounseling in humans and selective breeding in animal and plant …

A two-stage approximation for analysis of mixture genetic models in large pedigrees

D Habier, LR Totir, RL Fernando - Genetics, 2010 - academic.oup.com
Abstract Information from cosegregation of marker and QTL alleles, in addition to linkage
disequilibrium (LD), can improve genomic selection. Variance components linear models have …

A comparison of alternative methods to compute conditional genotype probabilities for genetic evaluation with finite locus models

LR Totir, RL Fernando, JCM Dekkers… - Genetics Selection …, 2003 - gse-journal.org
… [1] Bink MCAM, van Arendonk JAM, Quaas RL, Breeding value estimation with incomplete
… [31] Totir LR, Genetic evaluation with finite locus models, Ph.D. thesis, Iowa State University, …

The effect of using approximate gametic variance covariance matrices on marker assisted selection by BLUP

LR Totir, RL Fernando, JCM Dekkers… - Genetics Selection …, 2004 - gse-journal.org
Under additive inheritance, the Henderson mixed model equations (HMME) provide an
efficient approach to obtaining genetic evaluations by marker assisted best linear unbiased …

Algorithms to compute allele state and origin probabilities for QTL mapping.

RL Fernando, LR Totir, FVC Pita, C Stricker… - 2006 - cabidigitallibrary.org
QTL allele state and allele origin probabilities are used in linear model methods to map QTL.
When data are from complex pedigrees, MCMC methods are useful to compute these …

A study on the minimum number of loci required for genetic evaluation using a finite locus model

LR Totir, RL Fernando, JCM Dekkers… - Genetics Selection …, 2004 - gse-journal.org
For a finite locus model, Markov chain Monte Carlo (MCMC) methods can be used to estimate
the conditional mean of genotypic values given phenotypes, which is also known as the …

[PDF][PDF] Incorporating molecular information in breeding programmes: methodology.

RL Fernando, LR Totir - 2003 - cabidigitallibrary.org
RL Fernando and LR TotirRL Fernando and LR Totir … Comparison of conditional
means under finite locus models with BLUP evaluations indicate that a small number of loci …

Genomic selection

…, C Stricker, JCM Dekkers, LR Totir - … Scand Section A, 2007 - Taylor & Francis
Computer simulation was used to examine the relationship between the number of loci
included in the model and the accuracy of whole-genome methods for genetic evaluation. …