The identification and characterization of cis-regulatory DNA sequences and how they
function to coordinate responses to developmental and environmental cues is of paramount …

… Author links open overlay panel Adam J Bewick , Robert J Schmitz … Jim, RJ Schmitz …
RJ Schmitz, MD Schultz, MA Urich, JR Nery, M. Pelizzola, O. Libiger, A. …

Over the past few years the cost of DNA sequencing has plummeted while the numbers and
lengths of sequencing reads have increased. This sequencing revolution has led to …

Arabidopsis thaliana serves as a model organism for the study of fundamental physiological,
cellular, and molecular processes. It has also greatly advanced our understanding of …

Regulation of gene expression by DNA methylation is crucial for defining cellular identities
and coordinating organism-wide developmental programs in many organisms. In plants, …

Plants have unique features that evolved in response to their environments and ecosystems.
A full account of the complex cellular networks that underlie plant-specific functions is still …

… Schmitz, PhD … Author Affiliations: Department of Anesthesiology and Critical Care
Medicine and Center for Research on Health Care, University of Pittsburgh, Pittsburgh, Pa (Dr …

Cultivated peanut (Arachis hypogaea) is an allotetraploid with closely related subgenomes
of a total size of ∼2.7 Gb. This makes the assembly of chromosomal pseudomolecules very …

The epigenome orchestrates genome accessibility, functionality, and three-dimensional
structure. Because epigenetic variation can impact transcription and thus phenotypes, it may …

Epigenetic information, which may affect an organism’s phenotype, can be stored and
stably inherited in the form of cytosine DNA methylation. Changes in DNA methylation can …