User profiles for R. I. Wilson
Rachel I. WilsonProfessor of Neurobiology, Harvard Medical School Verified email at hms.harvard.edu Cited by 15272 |
Endocannabinoid signaling in the brain
RI Wilson, RA Nicoll - science, 2002 - science.org
The primary psychoactive ingredient in cannabis, Δ 9 -tetrahydrocannabinol (Δ 9 -THC),
affects the brain mainly by activating a specific receptor (CB1). CB1 is expressed at high levels …
affects the brain mainly by activating a specific receptor (CB1). CB1 is expressed at high levels …
Early events in olfactory processing
Olfactory space has a higher dimensionality than does any other class of sensory stimuli, and
the olfactory system receives input from an unusually large number of unique information …
the olfactory system receives input from an unusually large number of unique information …
Early Olfactory Processing in Drosophila: Mechanisms and Principles
RI Wilson - Annual review of neuroscience, 2013 - annualreviews.org
In the olfactory system of Drosophila melanogaster, it is relatively straightforward to target in
vivo measurements of neural activity to specific processing channels. This, together with the …
vivo measurements of neural activity to specific processing channels. This, together with the …
Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses
RI Wilson, RA Nicoll - Nature, 2001 - nature.com
Marijuana affects brain function primarily by activating the G-protein-coupled cannabinoid
receptor-1 (CB1) 1 , 2 , 3 , which is expressed throughout the brain at high levels 4 . Two …
receptor-1 (CB1) 1 , 2 , 3 , which is expressed throughout the brain at high levels 4 . Two …
Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly
For more than 100 years, the fruit fly Drosophila melanogaster has been one of the most
studied model organisms. Here, we present a single-cell atlas of the adult fly, Tabula …
studied model organisms. Here, we present a single-cell atlas of the adult fly, Tabula …
Oscillations and sparsening of odor representations in the mushroom body
In the insect olfactory system, oscillatory synchronization is functionally relevant and reflects
the coherent activation of dynamic neural assemblies. We examined the role of such …
the coherent activation of dynamic neural assemblies. We examined the role of such …
The fat embolism syndrome
AR Gurd, RI Wilson - The Journal of Bone & Joint Surgery …, 1974 - boneandjoint.org.uk
1. A distinction must be made between the fat embolism syndrome, a clinical entity, and fat
embolism demonstrated pathologically, which may be found after death following fracture with …
embolism demonstrated pathologically, which may be found after death following fracture with …
[HTML][HTML] painless, a Drosophila gene essential for nociception
We describe a paradigm for nociception in Drosophila. In response to the touch of a probe
heated above 38C, Drosophila larvae produce a stereotypical rolling behavior, unlike the …
heated above 38C, Drosophila larvae produce a stereotypical rolling behavior, unlike the …
[HTML][HTML] Presynaptic specificity of endocannabinoid signaling in the hippocampus
Endocannabinoids are retrograde messengers released by neurons to modulate the strength
of their synaptic inputs. Endocannabinoids are thought to mediate the suppression of …
of their synaptic inputs. Endocannabinoids are thought to mediate the suppression of …
Transformation of Olfactory Representations in the Drosophila Antennal Lobe
Molecular genetics has revealed a precise stereotypy in the projection of primary olfactory
sensory neurons onto secondary neurons. A major challenge is to understand how this …
sensory neurons onto secondary neurons. A major challenge is to understand how this …