In nanopore sequencing devices, electrolytic current signals are sensitive to base modifications,
such as 5-methylcytosine (5-mC). Here we quantified the strength of this effect for the …

High-throughput complementary DNA sequencing technologies have advanced our
understanding of transcriptome complexity and regulation. However, these methods lose …

Despite advances in sequencing, structural variants (SVs) remain difficult to reliably detect
due to the short read length (<300 bp) of 2nd generation sequencing. Not only do the reads (…

Mammalian genomes exhibit complex patterns of gene expression regulated, in part, by DNA
methylation. The advent of engineered DNA methyltransferases (MTases) to target DNA …

Background The release of the first reference genome of walnut (Juglans regia L.) enabled
many achievements in the characterization of walnut genetic and functional variation. …

… We replaced the entire 79 nt segment with a 50-GAAA-30 tetraloop and found that repression
of Pcas was maintained (Figure S3I), suggesting that this region is dispensable for tracr-L …

… We saved the output of the longest_path program into a file and resumed the execution of
MaSuRCA by re-running the auto-generated assemble.sh script. We note that in the current …

… Because we considered it likely that an enrichment in lipid metabolic genes could be a re- …
-like transcript noted from Illumina sequencing results. While humans express chitinase in the …

… pyogenes from phages by (1) limiting the number of infected cells that succumb to lysis or
lysogeny and (2) enhancing the survival of re-infected cells. Our work demonstrates a novel …

Hummingbirds are very well adapted to sustain efficient and rapid metabolic shifts. They
oxidize ingested nectar to directly fuel flight when foraging but have to switch to oxidizing stored …