Colorectal cancer (CRC) ranks third among the most commonly diagnosed cancers worldwide,
with wide geographical variation in incidence and mortality across the world. Despite …

… adequate performance (incompletely visualized segment—recommend re-examination;
residual polyp at margin—recommend resection and re-examination), it might be possible to …

BACKGROUND & AIMS: Heritable factors contribute to the development of colorectal cancer.
Identifying the genetic loci associated with colorectal tumor formation could elucidate the …

Earlier detection is key to reducing cancer deaths. Here, we describe a blood test that can
detect eight common cancer types through assessment of the levels of circulating proteins and …

Background We tested the hypothesis that dietary intervention can inhibit the development
of recurrent colorectal adenomas, which are precursors of most large-bowel cancers. …

Background The benefits of endoscopic testing for colorectal-cancer screening are uncertain.
We evaluated the effect of screening with flexible sigmoidoscopy on colorectal-cancer …

BACKGROUND: Abdominal obesity—an elevated level of visceral adipose tissue—has been
linked to colorectal cancer. Furthermore, elevated levels of visceral adipose tissue have …

BACKGROUND: Interval colorectal cancer (CRC) occasionally is detected in patients who
have recently undergone colonoscopy. Systematic evaluation of CRC detected after …

To further dissect the genetic architecture of colorectal cancer (CRC), we performed whole-genome
sequencing of 1,439 cases and 720 controls, imputed discovered sequence variants …

… Schoen, Department of Medicine, Mezzanine Level, C Wing, University of Pittsburgh …
This study was funded by the NCI grant P01 CA73743 to OJ Finn and RE Schoen, NIH grants …