User profiles for R. E. Lenski
Richard LenskiMicrobiology / EEB / Michigan State University Verified email at msu.edu Cited by 50219 |
The dynamics of molecular evolution over 60,000 generations
… Michael Desai, Richard Lenski and colleagues now report whole-genome sequencing at
500-generation intervals over the course of the 60,000 generations from the LTEE. Their …
500-generation intervals over the course of the 60,000 generations from the LTEE. Their …
Long-term experimental evolution in Escherichia coli. I. Adaptation and divergence during 2,000 generations
… coli are T5 resistant (RE Lenski, unpublished data) and most laboratory strains (eg, K12) are
T6 sensitive. In addition, both naturally occurring and laboratory strains of E. coli are almost …
T6 sensitive. In addition, both naturally occurring and laboratory strains of E. coli are almost …
Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coli
…, CZ Borland, RE Lenski - Proceedings of the …, 2008 - National Acad Sciences
… RE Lenski, Experimental studies of pleiotropy and epistasis in Escherichia coli. II.
Compensation for maladaptive pleiotropic effects associated with resistance to virus T4. …
Compensation for maladaptive pleiotropic effects associated with resistance to virus T4. …
Evolution experiments with microorganisms: the dynamics and genetic bases of adaptation
Microorganisms have been mutating and evolving on Earth for billions of years. Now, a field
of research has developed around the idea of using microorganisms to study evolution in …
of research has developed around the idea of using microorganisms to study evolution in …
Dynamics of adaptation and diversification: a 10,000-generation experiment with bacterial populations.
RE Lenski, M Travisano - Proceedings of the National …, 1994 - National Acad Sciences
We followed evolutionary change in 12 populations of Escherichia coli propagated for
10,000 generations in identical environments. Both morphology (cell size) and fitness (measured …
10,000 generations in identical environments. Both morphology (cell size) and fitness (measured …
Genome dynamics during experimental evolution
JE Barrick, RE Lenski - Nature Reviews Genetics, 2013 - nature.com
Evolutionary changes in organismal traits may occur either gradually or suddenly. However,
until recently, there has been little direct information about how phenotypic changes are …
until recently, there has been little direct information about how phenotypic changes are …
Genomic analysis of a key innovation in an experimental Escherichia coli population
… Here we report the results of extensive whole-genome re-sequencing that allowed us to
reconstruct the population’s history, identify mutations underlying the Cit + phenotype, and …
reconstruct the population’s history, identify mutations underlying the Cit + phenotype, and …
Experimental evolution
Experimental evolution is the study of evolutionary processes occurring in experimental
populations in response to conditions imposed by the experimenter. This research approach is …
populations in response to conditions imposed by the experimenter. This research approach is …
Genome evolution and adaptation in a long-term experiment with Escherichia coli
… Mutations in each genome were then identified using BRESEQ, a pipeline implemented in
Perl for analysing bacterial WGS re-sequencing data (JE Barrick, unpublished algorithm). The …
Perl for analysing bacterial WGS re-sequencing data (JE Barrick, unpublished algorithm). The …
The planned introduction of genetically engineered organisms: ecological considerations and recommendations
…, RK Colwell, YL Grossman, RE Hodson, RE Lenski… - Ecology, 1989 - Wiley Online Library
… Such resistance could reduce the efficacy of engineering the Bt toxin into agricultural …
Lenski, RE 1987. The infectious spread of engineered genes. Pages 99-124 in JR Fowle, III, …
Lenski, RE 1987. The infectious spread of engineered genes. Pages 99-124 in JR Fowle, III, …