The large collections of Arabidopsis thaliana sequence‐indexed T‐DNA insertion mutants
are among the most important resources to emerge from the sequencing of the genome. …

Deciphering the multiple layers of epigenetic regulation that control transcription is critical to
understanding how plants develop and respond to their environment. Using sequencing-by-…

The cistrome is the complete set of transcription factor (TF) binding sites (cis-elements) in an
organism, while an epicistrome incorporates tissue-specific DNA chemical modifications …

Epigenetic information, which may affect an organism’s phenotype, can be stored and
stably inherited in the form of cytosine DNA methylation. Changes in DNA methylation can …

The epigenome orchestrates genome accessibility, functionality, and three-dimensional
structure. Because epigenetic variation can impact transcription and thus phenotypes, it may …

MicroRNAs (miRNAs) and small interfering RNAs (siRNAs) are abundant endogenous
small RNAs (smRNAs) that control transcript expression through posttranscriptional gene …

Progress in sequencing, microfluidics, and analysis strategies has revolutionized the granularity
at which multicellular organisms can be studied. In particular, single-cell transcriptomics …

To enable low-cost, high-throughput generation of cistrome and epicistrome maps for any
organism, we developed DNA affinity purification sequencing (DAP-seq), a transcription factor (…

Single-cell transcriptome profiling of heterogeneous tissues can provide high-resolution
windows into developmental dynamics and environmental responses, but its application to …

Ethylene signaling in plants is mediated by a family of ethylene receptors related to bacterial
two‐component regulators. Expression in yeast of ethylene‐binding domains from the five …