User profiles for R. C. Jansen

ritsert jansen

Professor of Bioinformatics, Dean of Talent Development
Verified email at rug.nl
Cited by 22335

Genetical genomics: the added value from segregation

RC Jansen, JP Nap - TRENDS in Genetics, 2001 - cell.com
The recent successes of genome-wide expression profiling in biology tend to overlook the
power of genetics. We here propose a merger of genomics and genetics into ‘genetical …

Epigenome dynamics: a quantitative genetics perspective

F Johannes, V Colot, RC Jansen - Nature Reviews Genetics, 2008 - nature.com
Classically, quantitative geneticists have envisioned DNA sequence variants as the only
source of heritable phenotypes. This view should be revised in light of accumulating evidence …

Using complex plant pedigrees to map valuable genes

JL Jannink, MCAM Bink, RC Jansen - Trends in plant science, 2001 - cell.com
Statistical methods pioneered by human and animal geneticists use marker and pedigree
information to detect quantitative trait loci within complex pedigrees. These methods, adapted …

Systematic identification of trans eQTLs as putative drivers of known disease associations

…, H Grallert, T Meitinger, K Strauch, Y Li, RC Jansen… - Nature …, 2013 - nature.com
Identifying the downstream effects of disease-associated SNPs is challenging. To help
overcome this problem, we performed expression quantitative trait locus (eQTL) meta-analysis in …

High resolution of quantitative traits into multiple loci via interval mapping.

RC Jansen, P Stam - Genetics, 1994 - academic.oup.com
… Here we follow the method described by JANSEN (1993b), which is essentially a …
JANSEN, RC, 1993a Maximum likelihood in a generalized linear finite mixture model by …

Interval mapping of multiple quantitative trait loci.

RC Jansen - Genetics, 1993 - academic.oup.com
JANSEN (1 992) described a general mixture model for the case of multiple QTLs. Unfortunately,
the computation involved with all these methods is almost infeasible when the number …

Identification of the SAAT Gene Involved in Strawberry Flavor Biogenesis by Use of DNA Microarrays

…, RCH De Vos, H Van Der Voet, RC Jansen… - The Plant …, 2000 - academic.oup.com
Fruit flavor is a result of a complex mixture of numerous compounds. The formation of these
compounds is closely correlated with the metabolic changes occurring during fruit maturation…

The genetics of plant metabolism

…, RD Hall, RJ Bino, LHW Van Der Plas, RC Jansen… - Nature …, 2006 - nature.com
Variation for metabolite composition and content is often observed in plants. However, it is
poorly understood to what extent this variation has a genetic basis. Here, we describe the …

R/qtl: high-throughput multiple QTL mapping

D Arends, P Prins, RC Jansen, KW Broman - Bioinformatics, 2010 - academic.oup.com
Motivation: R/qtl is free and powerful software for mapping and exploring quantitative trait
loci (QTL). R/qtl provides a fully comprehensive range of methods for a wide range of …

Mapping the epigenetic basis of complex traits

…, F Hospital, JM Aury, P Wincker, F Roudier, RC Jansen… - Science, 2014 - science.org
Quantifying the impact of heritable epigenetic variation on complex traits is an emerging
challenge in population genetics. Here, we analyze a population of isogenic Arabidopsis lines …