User profiles for R. C. Jansen
ritsert jansenProfessor of Bioinformatics, Dean of Talent Development Verified email at rug.nl Cited by 22335 |
Genetical genomics: the added value from segregation
RC Jansen, JP Nap - TRENDS in Genetics, 2001 - cell.com
The recent successes of genome-wide expression profiling in biology tend to overlook the
power of genetics. We here propose a merger of genomics and genetics into ‘genetical …
power of genetics. We here propose a merger of genomics and genetics into ‘genetical …
Epigenome dynamics: a quantitative genetics perspective
Classically, quantitative geneticists have envisioned DNA sequence variants as the only
source of heritable phenotypes. This view should be revised in light of accumulating evidence …
source of heritable phenotypes. This view should be revised in light of accumulating evidence …
Using complex plant pedigrees to map valuable genes
JL Jannink, MCAM Bink, RC Jansen - Trends in plant science, 2001 - cell.com
Statistical methods pioneered by human and animal geneticists use marker and pedigree
information to detect quantitative trait loci within complex pedigrees. These methods, adapted …
information to detect quantitative trait loci within complex pedigrees. These methods, adapted …
Systematic identification of trans eQTLs as putative drivers of known disease associations
Identifying the downstream effects of disease-associated SNPs is challenging. To help
overcome this problem, we performed expression quantitative trait locus (eQTL) meta-analysis in …
overcome this problem, we performed expression quantitative trait locus (eQTL) meta-analysis in …
High resolution of quantitative traits into multiple loci via interval mapping.
RC Jansen, P Stam - Genetics, 1994 - academic.oup.com
… Here we follow the method described by JANSEN (1993b), which is essentially a …
JANSEN, RC, 1993a Maximum likelihood in a generalized linear finite mixture model by …
JANSEN, RC, 1993a Maximum likelihood in a generalized linear finite mixture model by …
Interval mapping of multiple quantitative trait loci.
RC Jansen - Genetics, 1993 - academic.oup.com
… JANSEN (1 992) described a general mixture model for the case of multiple QTLs. Unfortunately,
the computation involved with all these methods is almost infeasible when the number …
the computation involved with all these methods is almost infeasible when the number …
Identification of the SAAT Gene Involved in Strawberry Flavor Biogenesis by Use of DNA Microarrays
Fruit flavor is a result of a complex mixture of numerous compounds. The formation of these
compounds is closely correlated with the metabolic changes occurring during fruit maturation…
compounds is closely correlated with the metabolic changes occurring during fruit maturation…
The genetics of plant metabolism
Variation for metabolite composition and content is often observed in plants. However, it is
poorly understood to what extent this variation has a genetic basis. Here, we describe the …
poorly understood to what extent this variation has a genetic basis. Here, we describe the …
R/qtl: high-throughput multiple QTL mapping
Motivation: R/qtl is free and powerful software for mapping and exploring quantitative trait
loci (QTL). R/qtl provides a fully comprehensive range of methods for a wide range of …
loci (QTL). R/qtl provides a fully comprehensive range of methods for a wide range of …
Mapping the epigenetic basis of complex traits
Quantifying the impact of heritable epigenetic variation on complex traits is an emerging
challenge in population genetics. Here, we analyze a population of isogenic Arabidopsis lines …
challenge in population genetics. Here, we analyze a population of isogenic Arabidopsis lines …